Literature DB >> 2196386

Hepatitis B virus X protein produced in Escherichia coli is biologically functional.

S Jameel1, A Siddiqui, H F Maguire, K V Rao.   

Abstract

The hepatitis B virus X gene product trans activates transcription from a variety of viral and cellular regulatory elements. We expressed the complete, nonfused X protein in Escherichia coli and showed it to be active in trans activating a human immunodeficiency virus long terminal repeat-linked chloramphenicol acetyltransferase reporter gene.

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Year:  1990        PMID： 2196386      PMCID： PMC249692     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  12 in total

Review 1.  NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control.

Authors:  M J Lenardo; D Baltimore
Journal:  Cell       Date:  1989-07-28       Impact factor: 41.582

2.  Transcriptional trans-activating function of hepatitis B virus.

Authors:  J S Twu; R H Schloemer
Journal:  J Virol       Date:  1987-11       Impact factor: 5.103

3.  trans-activation of viral enhancers by the hepatitis B virus X protein.

Authors:  D F Spandau; C H Lee
Journal:  J Virol       Date:  1988-02       Impact factor: 5.103

4.  Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein.

Authors:  M Green; P M Loewenstein
Journal:  Cell       Date:  1988-12-23       Impact factor: 41.582

5.  The HBV X-ORF encodes a transactivator: a potential factor in viral hepatocarcinogenesis.

Authors:  P Zahm; P H Hofschneider; R Koshy
Journal:  Oncogene       Date:  1988-08       Impact factor: 9.867

6.  Cellular uptake of the tat protein from human immunodeficiency virus.

Authors:  A D Frankel; C O Pabo
Journal:  Cell       Date:  1988-12-23       Impact factor: 41.582

7.  Identification of a region within the human immunodeficiency virus type 1 long terminal repeat that is essential for transactivation by the hepatitis B virus gene X.

Authors:  J S Twu; C A Rosen; W A Haseltine; W S Robinson
Journal:  J Virol       Date:  1989-06       Impact factor: 5.103

8.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

Authors:  C M Gorman; L F Moffat; B H Howard
Journal:  Mol Cell Biol       Date:  1982-09       Impact factor: 4.272

9.  A transactivating function encoded in the hepatitis B virus X gene is conserved in the integrated state.

Authors:  M Wollersheim; U Debelka; P H Hofschneider
Journal:  Oncogene       Date:  1988-11       Impact factor: 9.867

Review 10.  The hepatitis B virus.

Authors:  P Tiollais; C Pourcel; A Dejean
Journal:  Nature       Date:  1985 Oct 10-16       Impact factor: 49.962
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  12 in total

1.  Alternate translation initiation on hepatitis B virus X mRNA produces multiple polypeptides that differentially transactivate class II and III promoters.

Authors:  L Kwee; R Lucito; B Aufiero; R J Schneider
Journal:  J Virol       Date:  1992-07       Impact factor: 5.103

2.  XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation.

Authors:  N Kuzhandaivelu; Y S Cong; C Inouye; W M Yang; E Seto
Journal:  Nucleic Acids Res       Date:  1996-12-01       Impact factor: 16.971

3.  Disruption of the function of tumor-suppressor gene p53 by the hepatitis B virus X protein and hepatocarcinogenesis.

Authors:  S Takada; N Tsuchida; M Kobayashi; K Koike
Journal:  J Cancer Res Clin Oncol       Date:  1995       Impact factor: 4.553

4.  The hepatitis B virus X protein targets the basic region-leucine zipper domain of CREB.

Authors:  J S Williams; O M Andrisani
Journal:  Proc Natl Acad Sci U S A       Date:  1995-04-25       Impact factor: 11.205

5.  Sustained activation of mitogen-activated protein kinases and activator protein 1 by the hepatitis B virus X protein in mouse hepatocytes in vivo.

Authors:  R Nijhara; S S Jana; S K Goswami; A Rana; S S Majumdar; V Kumar; D P Sarkar
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

6.  A truncated mutant (residues 58-140) of the hepatitis B virus X protein retains transactivation function.

Authors:  V Kumar; N Jayasuryan; R Kumar
Journal:  Proc Natl Acad Sci U S A       Date:  1996-05-28       Impact factor: 11.205

7.  Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C.

Authors:  R Lucito; R J Schneider
Journal:  J Virol       Date:  1992-02       Impact factor: 5.103

8.  RPS3a over-expressed in HBV-associated hepatocellular carcinoma enhances the HBx-induced NF-κB signaling via its novel chaperoning function.

Authors:  Keo-Heun Lim; Kyun-Hwan Kim; Seong Il Choi; Eun-Sook Park; Seung Hwa Park; Kisun Ryu; Yong Kwang Park; So Young Kwon; Sung-Il Yang; Han Chu Lee; In-Kyung Sung; Baik L Seong
Journal:  PLoS One       Date:  2011-08-16       Impact factor: 3.240

9.  Non-chromatographic Method for the Hepatitis B Virus X Protein Using Elastin-Like Polypeptide Fusion Protein.

Authors:  Soon-Hwan Kwon; Hyeseong Cho
Journal:  Osong Public Health Res Perspect       Date:  2012-06

10.  High-level expression and large-scale preparation of soluble HBx antigen from Escherichia coli.

Authors:  Dong Liu; Liyun Zou; Wanling Li; Li Wang; Yuzhang Wu
Journal:  Biotechnol Appl Biochem       Date:  2009-09-24       Impact factor: 2.431
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