| Literature DB >> 21963739 |
Kayoko Ikegawa1, Masayuki Hanaoka, Atsuhito Ushiki, Hiroshi Yamamoto, Keishi Kubo.
Abstract
A 66-year-old woman rheumatoid arthritis was treated with methotrexate and tocilizumab. Chest radiography revealed bilateral consolidation of an upper lesion in the lung. Laboratory data indicated a hepatic disorder and increased eosinophils. Transbronchial lung biopsy specimens showed organizing pneumonia. Infection was unfavorable based on culture and PCR. Drug lymphocyte stimulation test showed positive results both for methotrexate and tocilizumab. We were concerned that her pneumonitis was drug-induced. And the symptoms appeared after the infusion of tocilizumab. Here, we report a case of tocilizumab-induced organizing pneumonia.Entities:
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Year: 2011 PMID： 21963739 DOI： 10.2169/internalmedicine.50.5497
Source DB: PubMed Journal: Intern Med ISSN： 0918-2918 Impact factor: 1.271