Literature DB >> 21962500

Genetics and genomics to the clinic: a long road ahead.

David Ginsburg1.   

Abstract

Advances in genomic technology have produced an explosion of new information about the genetic basis for human disease, fueling extraordinarily high expectations for improved treatments. This perspective will take brief stock of what genetics/genomics have brought to clinical practice to date and what we might expect for the future.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21962500     DOI: 10.1016/j.cell.2011.09.013

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  4 in total

1.  Molecular mechanism-based model to enhance outcomes of dietary intervention studies for disease prevention.

Authors:  Moul Dey
Journal:  J Mol Biochem       Date:  2012-10-16

Review 2.  Atherosclerosis, inflammation, genetics, and stem cells: 2012 update.

Authors:  Pascal J Goldschmidt-Clermont; Chunming Dong; David M Seo; Omaida C Velazquez
Journal:  Curr Atheroscler Rep       Date:  2012-06       Impact factor: 5.113

3.  Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity.

Authors:  Wangko Lundström; Steven Highfill; Scott T R Walsh; Stephanie Beq; Elizabeth Morse; Ingrid Kockum; Lars Alfredsson; Tomas Olsson; Jan Hillert; Crystal L Mackall
Journal:  Proc Natl Acad Sci U S A       Date:  2013-04-22       Impact factor: 11.205

Review 4.  Contrasting genetic architectures in different mouse reference populations used for studying complex traits.

Authors:  David A Buchner; Joseph H Nadeau
Journal:  Genome Res       Date:  2015-05-07       Impact factor: 9.043

  4 in total

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