INTRODUCTION: Peripheral primitive neuroectodermal tumor of the cervix uteri is extremely rare. Between 1987 and 2010, there were only nine cases reported in the English literature, with considerably different management policies. CASE PRESENTATION: A 45-year-old Iranian woman presented to our facility with a primitive neuroectodermal tumor of the cervix uteri. Her clinical stage IB2 tumor was treated successfully with chemotherapy. Our patient underwent radical hysterectomy. There was no trace of the tumor after four years of follow-up. CONCLUSIONS: According to current knowledge, primitive neuroectodermal tumors belong to the Ewing's sarcoma family, and the improvement of treatment outcome in our patient was due to dose-intensive neoadjuvant chemotherapy, surgery and consolidation chemotherapy in accordance with the protocol for bony Ewing's sarcoma.
INTRODUCTION: Peripheral primitive neuroectodermal tumor of the cervix uteri is extremely rare. Between 1987 and 2010, there were only nine cases reported in the English literature, with considerably different management policies. CASE PRESENTATION: A 45-year-old Iranian woman presented to our facility with a primitive neuroectodermal tumor of the cervix uteri. Her clinical stage IB2tumor was treated successfully with chemotherapy. Our patient underwent radical hysterectomy. There was no trace of the tumor after four years of follow-up. CONCLUSIONS: According to current knowledge, primitive neuroectodermal tumors belong to the Ewing's sarcoma family, and the improvement of treatment outcome in our patient was due to dose-intensive neoadjuvant chemotherapy, surgery and consolidation chemotherapy in accordance with the protocol for bony Ewing's sarcoma.
Authors: P Pauwels; P Ambros; C Hattinger; M Lammens; P Dal Cin; J Ribot; A Struyk; H van den Berghe Journal: Virchows Arch Date: 2000-01 Impact factor: 4.064
Authors: G Cenacchi; G Pasquinelli; L Montanaro; S Cerasoli; M Vici; M Bisceglia; F Giangaspero; G N Martinelli; M Derenzini Journal: Int J Gynecol Pathol Date: 1998-01 Impact factor: 2.762
Authors: Rosalba De Nola; Edoardo Di Naro; Luca Maria Schonauer; Giuseppe Lucarelli; Michele Battaglia; Maria Grazia Fiore; Salvatore Andrea Mastrolia; Giuseppe Loverro Journal: Medicine (Baltimore) Date: 2018-01 Impact factor: 1.889