Literature DB >> 21959766

Classic in vivo cancer models: three examples of mouse models used in experimental therapeutics.

Anna Kruczynski1, Bridget T Hill.   

Abstract

Transplantable animal tumors have been associated with the discovery of most clinically active anticancer agents. They are still useful today in conducting detailed evaluations of new candidate anticancer drugs. Three protocols relating to transplantable experimental tumors are described in this unit. Included are the intravenously-implanted murine P388 leukemia, the subcutaneously-implanted murine B16 melanoma and two examples of subcutaneously-implanted human tumor xenografts, the LX-1 (lung) and MX-1 (breast) tumors.

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Year:  2002        PMID： 21959766     DOI： 10.1002/0471141755.ph0524s15

Source DB:  PubMed          Journal:  Curr Protoc Pharmacol        ISSN： 1934-8282


  7 in total

1.  Combination central tolerance and peripheral checkpoint blockade unleashes antimelanoma immunity.

Authors:  Pearl Bakhru; Meng-Lei Zhu; Hsing-Hui Wang; Lee K Hong; Imran Khan; Maria Mouchess; Ajay S Gulati; Joshua Starmer; Yafei Hou; David Sailer; Sandra Lee; Fengmin Zhao; John M Kirkwood; Stergios Moschos; Lawrence Fong; Mark S Anderson; Maureen A Su
Journal:  JCI Insight       Date:  2017-09-21

2.  Aire deficiency promotes TRP-1-specific immune rejection of melanoma.

Authors:  Meng-Lei Zhu; Anil Nagavalli; Maureen A Su
Journal:  Cancer Res       Date:  2013-01-31       Impact factor: 12.701

Review 3.  Zebrafish tumor assays: the state of transplantation.

Authors:  Alison M Taylor; Leonard I Zon
Journal:  Zebrafish       Date:  2009-12       Impact factor: 1.985

4.  Preparation, characterisation and preliminary antitumour activity evaluation of a novel nanoparticulate system based on a cisplatin-hyaluronate complex and N-trimethyl chitosan.

Authors:  Sergio Cafaggi; Eleonora Russo; Rossana Stefani; Brunella Parodi; Gabriele Caviglioli; Greta Sillo; Angela Bisio; Cinzia Aiello; Maurizio Viale
Journal:  Invest New Drugs       Date:  2009-12-29       Impact factor: 3.850

5.  The Tumor-Selective Cytotoxic Agent β-Lapachone is a Potent Inhibitor of IDO1.

Authors:  Hollie E Flick; Judith M Lalonde; William P Malachowski; Alexander J Muller
Journal:  Int J Tryptophan Res       Date:  2013-08-19

6.  Lipodox® (generic doxorubicin hydrochloride liposome injection): in vivo efficacy and bioequivalence versus Caelyx® (doxorubicin hydrochloride liposome injection) in human mammary carcinoma (MX-1) xenograft and syngeneic fibrosarcoma (WEHI 164) mouse models.

Authors:  Vinod Burade; Subhas Bhowmick; Kuntal Maiti; Rishit Zalawadia; Harry Ruan; Rajamannar Thennati
Journal:  BMC Cancer       Date:  2017-06-06       Impact factor: 4.430

7.  Zebrafish xenotransplantation model for cancer stem-like cell study and high-throughput screening of inhibitors.

Authors:  Beibei Zhang; Yasuhito Shimada; Junya Kuroyanagi; Yuhei Nishimura; Noriko Umemoto; Tsuyoshi Nomoto; Taichi Shintou; Takeshi Miyazaki; Toshio Tanaka
Journal:  Tumour Biol       Date:  2014-09-11
  7 in total

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