| Literature DB >> 2195744 |
J Muraki1, J C Addonizio, M S Choudhury, J Fischer, M Eshghi, M M Davidian, L R Shapiro, P L Wilmot, G R Nagamatsu, J W Chiao.
Abstract
The establishment of a new human prostatic cancer cell line is described. This cell line was derived from a poorly to moderately differentiated prostatic adenocarcinoma. It has been maintained in tissue culture for fourteen months and has been passed fifty-two times. This cell line has an ability to form colonies in soft agar suspension cultures, and also is transplantable to nude mice. Tumors grown in nude mice revealed a poorly differentiated adenocarcinoma with positive PSA staining. Acid phosphatase activity was detected in freeze-thawed cells by enzymatic assay. A karyotype analysis demonstrated aneuploidy with a model chromosomal number of 69 and six marker chromosomes.Entities:
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Year: 1990 PMID: 2195744 DOI: 10.1016/0090-4295(90)80319-i
Source DB: PubMed Journal: Urology ISSN: 0090-4295 Impact factor: 2.649