Literature DB >> 21956802

Electrophysiological analysis of heterologously expressed Kv and SK/IK potassium channels.

Neil A Castle1, Alan D Wickenden, Anruo Zou.   

Abstract

This unit describes protocols to aid investigators in determining the electrophysiological and pharmacological profile of heterologously expressed voltage or calcium-activated potassium channels belonging to the Kv1.x and SK/IK gene families. Protocols for data acquisition as well as analysis are provided.

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Year:  2003        PMID: 21956802     DOI: 10.1002/0471141755.ph1105s20

Source DB:  PubMed          Journal:  Curr Protoc Pharmacol        ISSN: 1934-8282


  2 in total

1.  PF-06526290 can both enhance and inhibit conduction through voltage-gated sodium channels.

Authors:  Lingxin Wang; Shannon G Zellmer; David M Printzenhoff; Neil A Castle
Journal:  Br J Pharmacol       Date:  2018-06-03       Impact factor: 8.739

2.  Addition of a single methyl group to a small molecule sodium channel inhibitor introduces a new mode of gating modulation.

Authors:  Lingxin Wang; Shannon G Zellmer; David M Printzenhoff; Neil A Castle
Journal:  Br J Pharmacol       Date:  2015-10-15       Impact factor: 8.739

  2 in total

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