DESIGN: A prospective, randomized, open study. The regional technique used was not blinded. SETTING: A university teaching hospital. PARTICIPANTS: Forty-eight patients undergoingvideo-assisted thoracoscopic surgery (VATS) for tumor resection. INTERVENTIONS: Patients received either continuous extrapleural block or continuous epidural block using ropivacaine for a period of 60 hours after surgery. MEASUREMENTS AND MAIN RESULTS: To evaluate postoperative pain control, the primary and secondary endpoints were the visual analog scale (VAS) on movement and the amount of rescue analgesia, respectively. There were no significant differences between the extrapleural and epidural block groups with regard to VAS at rest and during movement assessed at 4, 12, 24, 36, and 48 hours after surgery, dosage of intravenous morphine (extrapleural: 12.9 ± 11.3, epidural: 10.2 ± 6.9 mg), supplemental nonsteroidal anti-inflammatory drugs, incidence of postoperative nausea and vomiting (extrapleural: 12/20, epidural: 11/20), postoperative ambulation (extrapleural: 18 at postoperative day [POD] 1 and 20 at POD 2, epidural: 19 at POD 1 and 20 at POD 2) and hospital stay after surgery (extrapleural: 12.7 ± 6.3, epidural: 12.6 ± 4.7 days). CONCLUSIONS: Although this study did not show the superiority of continuous extrapleural block relative to continuous epidural in VATS patients, the results suggest that both methods provided effective analgesia with a relatively small dose of rescue morphine. Although the analgesic effects of these techniques were comparable, extrapleural block has the advantage of safety and precise placement of the catheter and can be considered an alternative to epidural block in VATS patients.
RCT Entities:
DESIGN: A prospective, randomized, open study. The regional technique used was not blinded. SETTING: A university teaching hospital. PARTICIPANTS: Forty-eight patients undergoing video-assisted thoracoscopic surgery (VATS) for tumor resection. INTERVENTIONS:Patients received either continuous extrapleural block or continuous epidural block using ropivacaine for a period of 60 hours after surgery. MEASUREMENTS AND MAIN RESULTS: To evaluate postoperative pain control, the primary and secondary endpoints were the visual analog scale (VAS) on movement and the amount of rescue analgesia, respectively. There were no significant differences between the extrapleural and epidural block groups with regard to VAS at rest and during movement assessed at 4, 12, 24, 36, and 48 hours after surgery, dosage of intravenous morphine (extrapleural: 12.9 ± 11.3, epidural: 10.2 ± 6.9 mg), supplemental nonsteroidal anti-inflammatory drugs, incidence of postoperative nausea and vomiting (extrapleural: 12/20, epidural: 11/20), postoperative ambulation (extrapleural: 18 at postoperative day [POD] 1 and 20 at POD 2, epidural: 19 at POD 1 and 20 at POD 2) and hospital stay after surgery (extrapleural: 12.7 ± 6.3, epidural: 12.6 ± 4.7 days). CONCLUSIONS: Although this study did not show the superiority of continuous extrapleural block relative to continuous epidural in VATS patients, the results suggest that both methods provided effective analgesia with a relatively small dose of rescue morphine. Although the analgesic effects of these techniques were comparable, extrapleural block has the advantage of safety and precise placement of the catheter and can be considered an alternative to epidural block in VATS patients.
Authors: Chang Young Lee; Kyoung Shik Narm; Jin Gu Lee; Hyo Chae Paik; Kyung Young Chung; Ha Young Shin; Ha Young Yeom; Dae Joon Kim Journal: J Thorac Dis Date: 2018-06 Impact factor: 2.895
Authors: Jelle E Bousema; Esther M Dias; Sander M Hagen; Bastiaan Govaert; Patrick Meijer; Frank J C van den Broek Journal: J Cardiothorac Surg Date: 2019-10-22 Impact factor: 1.637