| Literature DB >> 21955440 |
Marja Kik1, An Martel2, Annemarieke Spitzen-van der Sluijs3, Frank Pasmans2, Peter Wohlsein4, Andrea Gröne5, Jolianne M Rijks5.
Abstract
In 2010, a mass die-off of over 1000 wild water frogs (Pelophylax spp.) and at least 10 common newts (Lissotriton vulgaris) occurred in a pond in The Netherlands. Haemorrhagic disease with hepatomegaly and splenomegaly was evident. Microscopically, multiple organs presented cells with multifocal intracytoplasmic inclusion bodies, in which ranavirus-like particles were demonstrated ultrastructurally. All specimens examined tested positive for ranavirus by PCR. The sequence obtained showed a 100% identity with the one deposited for common midwife toad virus (CMTV). This is the first report of ranavirus-associated mortality in wild amphibian populations in The Netherlands. It is also the first time CMTV or a CMTV-like virus has been reported in these two species in the adult stage and outside of Spain.Entities:
Mesh：
Year: 2011 PMID： 21955440 DOI： 10.1016/j.tvjl.2011.08.031
Source DB: PubMed Journal: Vet J ISSN： 1090-0233 Impact factor: 2.688