MAPLSC: a novel multi-class classifier for medical diagnosis.

Analysis of clinical records contributes to the Traditional Chinese Medicine (TCM) experience expansion and techniques promotion. More than two diagnostic classes (diagnostic syndromes) in the clinical records raise a popular data mining problem: multi-value classification. In this paper, we propose a novel multi-class classifier, named Multiple Asymmetric Partial Least Squares Classifier (MAPLSC). MAPLSC attempts to be robust facing imbalanced data distribution in the multi-value classification. Elaborated comparisons with other seven state-of-the-art methods on two TCM clinical datasets and four public microarray datasets demonstrate MAPLSC's remarkable improvements.