Literature DB >> 21953501

Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis.

Christopher Lieu1, John Heymach, Michael Overman, Hai Tran, Scott Kopetz.   

Abstract

Fibroblast growth factor (FGF) signaling regulates cell proliferation, differentiation, survival, angiogenesis, and wound healing. Compelling evidence for deregulated FGF signaling in tumorigenesis continues to emerge, and a growing body of research suggests that FGF may also play an integral role in the resistance to anti-VEGF therapy. Although agents targeting FGF signaling are early in development, the potential to target both the VEGF and FGF pathways may translate into improvements in the clinical care of cancer patients. ©2011 AACR

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Year:  2011        PMID： 21953501      PMCID： PMC5562355          DOI： 10.1158/1078-0432.CCR-11-0659

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  104 in total

Review 1.  Evolution of the Fgf and Fgfr gene families.

Authors:  Nobuyuki Itoh; David M Ornitz
Journal:  Trends Genet       Date:  2004-11       Impact factor: 11.639

Review 2.  The heparan sulfate-fibroblast growth factor family: diversity of structure and function.

Authors:  W L McKeehan; F Wang; M Kan
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1998

3.  Correlation of bFGF, FGFR-1 and VEGF expression with vascularity and malignancy of human astrocytomas.

Authors:  X W Bian; L L Du; J Q Shi; Y S Cheng; F X Liu
Journal:  Anal Quant Cytol Histol       Date:  2000-06       Impact factor: 0.302

4.  Expression of basic fibroblast growth factor and its receptors by head and neck squamous carcinoma tumor and vascular endothelial cells.

Authors:  F R Dellacono; J Spiro; R Eisma; D Kreutzer
Journal:  Am J Surg       Date:  1997-11       Impact factor: 2.565

5.  FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival.

Authors:  Kaiko Kunii; Lenora Davis; Julie Gorenstein; Harold Hatch; Masakazu Yashiro; Alessandra Di Bacco; Cem Elbi; Bart Lutterbach
Journal:  Cancer Res       Date:  2008-04-01       Impact factor: 12.701

6.  Plasma basic fibroblast growth factor levels in colorectal cancer: a clinically useful assay?

Authors:  M L George; M G Tutton; A M Abulafi; S A Eccles; R I Swift
Journal:  Clin Exp Metastasis       Date:  2002       Impact factor: 5.150

7.  Interaction of high-molecular-weight basic fibroblast growth factor with endothelium: biological activity and intracellular fate of human recombinant M(r) 24,000 bFGF.

Authors:  A Gualandris; C Urbinati; M Rusnati; M Ziche; M Presta
Journal:  J Cell Physiol       Date:  1994-10       Impact factor: 6.384

8.  Endogenous basic fibroblast growth factor is implicated in the vascularization of the chick embryo chorioallantoic membrane.

Authors:  D Ribatti; C Urbinati; B Nico; M Rusnati; L Roncali; M Presta
Journal:  Dev Biol       Date:  1995-07       Impact factor: 3.582

9.  Patterns of somatic mutation in human cancer genomes.

Authors:  Christopher Greenman; Philip Stephens; Raffaella Smith; Gillian L Dalgliesh; Christopher Hunter; Graham Bignell; Helen Davies; Jon Teague; Adam Butler; Claire Stevens; Sarah Edkins; Sarah O'Meara; Imre Vastrik; Esther E Schmidt; Tim Avis; Syd Barthorpe; Gurpreet Bhamra; Gemma Buck; Bhudipa Choudhury; Jody Clements; Jennifer Cole; Ed Dicks; Simon Forbes; Kris Gray; Kelly Halliday; Rachel Harrison; Katy Hills; Jon Hinton; Andy Jenkinson; David Jones; Andy Menzies; Tatiana Mironenko; Janet Perry; Keiran Raine; Dave Richardson; Rebecca Shepherd; Alexandra Small; Calli Tofts; Jennifer Varian; Tony Webb; Sofie West; Sara Widaa; Andy Yates; Daniel P Cahill; David N Louis; Peter Goldstraw; Andrew G Nicholson; Francis Brasseur; Leendert Looijenga; Barbara L Weber; Yoke-Eng Chiew; Anna DeFazio; Mel F Greaves; Anthony R Green; Peter Campbell; Ewan Birney; Douglas F Easton; Georgia Chenevix-Trench; Min-Han Tan; Sok Kean Khoo; Bin Tean Teh; Siu Tsan Yuen; Suet Yi Leung; Richard Wooster; P Andrew Futreal; Michael R Stratton
Journal:  Nature       Date:  2007-03-08       Impact factor: 49.962

Review 10.  Fibroblast growth factors.

Authors:  D M Ornitz; N Itoh
Journal:  Genome Biol       Date:  2001-03-09       Impact factor: 13.583
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  104 in total

1.  Understanding and targeting resistance to anti-angiogenic therapies.

Authors:  Jeffrey M Clarke; Herbert I Hurwitz
Journal:  J Gastrointest Oncol       Date:  2013-09

2.  The role of FGF2 in migration and tubulogenesis of endothelial progenitor cells in relation to pro-angiogenic growth factor production.

Authors:  Monika Litwin; Agata Radwańska; Maria Paprocka; Claudine Kieda; Tadeusz Dobosz; Wojciech Witkiewicz; Dagmara Baczyńska
Journal:  Mol Cell Biochem       Date:  2015-08-28       Impact factor: 3.396

3.  Angiopoietin-1 prevents severe bleeding complications induced by heparin-like drugs and fibroblast growth factor-2 in mice.

Authors:  Marina Jerebtsova; Jharna R Das; Pingtao Tang; Edward Wong; Patricio E Ray
Journal:  Am J Physiol Heart Circ Physiol       Date:  2015-08-14       Impact factor: 4.733

Review 4.  FGF receptor inhibitors: role in cancer therapy.

Authors:  Gennaro Daniele; Jesus Corral; L Rhoda Molife; Johann S de Bono
Journal:  Curr Oncol Rep       Date:  2012-04       Impact factor: 5.075

5.  ECOG phase II trial of graded-dose peginterferon α-2b in patients with metastatic melanoma overexpressing basic fibroblast growth factor (E2602).

Authors:  Ronald S Go; Sandra J Lee; Donghoon Shin; Steven M Callister; Dean A Jobe; Robert M Conry; Ahmad A Tarhini; John M Kirkwood
Journal:  Clin Cancer Res       Date:  2013-10-11       Impact factor: 12.531

6.  Anti-Vasculogenic Activity of a Polysaccharide Derived from Brittle Star via Inhibition of VEGF, Paxillin and MMP-9.

Authors:  Javad Baharara; Elaheh Amini; Marziyeh Musavi
Journal:  Iran J Biotechnol       Date:  2017-09-27       Impact factor: 1.671

7.  Thermal inkjet bioprinting triggers the activation of the VEGF pathway in human microvascular endothelial cells in vitro.

Authors:  Luis H Solis; Yoshira Ayala; Susana Portillo; Armando Varela-Ramirez; Renato Aguilera; Thomas Boland
Journal:  Biofabrication       Date:  2019-07-09       Impact factor: 9.954

Review 8.  Targeting the Angiopoietin-2/Tie-2 axis in conjunction with VEGF signal interference.

Authors:  Nikolett M Biel; Dietmar W Siemann
Journal:  Cancer Lett       Date:  2014-10-12       Impact factor: 8.679

9.  Pericytes modulate endothelial sprouting.

Authors:  William G Chang; Jillian W Andrejecsk; Martin S Kluger; W Mark Saltzman; Jordan S Pober
Journal:  Cardiovasc Res       Date:  2013-09-16       Impact factor: 10.787

10.  Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2.

Authors:  Joao Incio; Jennifer A Ligibel; Daniel T McManus; Priya Suboj; Keehoon Jung; Kosuke Kawaguchi; Matthias Pinter; Suboj Babykutty; Shan M Chin; Trupti D Vardam; Yuhui Huang; Nuh N Rahbari; Sylvie Roberge; Dannie Wang; Igor L Gomes-Santos; Stefan B Puchner; Christopher L Schlett; Udo Hoffmman; Marek Ancukiewicz; Sara M Tolaney; Ian E Krop; Dan G Duda; Yves Boucher; Dai Fukumura; Rakesh K Jain
Journal:  Sci Transl Med       Date:  2018-03-14       Impact factor: 17.956
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