| Literature DB >> 21952799 |
Siamon Gordon1, Jörg Hamann, Hsi-Hsien Lin, Martin Stacey.
Abstract
The F4/80 monoclonal antibody was first reported in this journal 30 years ago (Eur. J. Immunol. 1981. 11: 805-815). F4/80 has become a widely used marker for monocytes and many, but not all, tissue macrophages in the mouse. F4/80 is a member of the EGF-TM7 family of leukocyte plasma membrane heptahelical molecules, which includes CD97 and EMR2. This Viewpoint summarises current knowledge of the expression, structure and functions of the EGF-TM7 family, as part of a larger family of tissue adhesion-GPCRs.Entities:
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Year: 2011 PMID： 21952799 DOI： 10.1002/eji.201141715
Source DB: PubMed Journal: Eur J Immunol ISSN： 0014-2980 Impact factor: 5.532