| Literature DB >> 21951069 |
Konstanze Miehle1, Holger Stepan, Mathias Fasshauer.
Abstract
Proteins secreted from adipocytes - so-called adipokines - influence metabolic and vascular function. Recent data suggest that various adipokines are dysregulated in gestational diabetes mellitus (GDM) and pre-eclampsia (PE) and might be of pathophysiological and prognostic significance in these complications of pregnancy. This review gives an overview on the regulation and pathophysiology of leptin and adiponectin in GDM and PE. Furthermore, data on novel adipokines including resistin, visfatin, retinol-binding protein 4 and vaspin are summarized.Entities:
Mesh:
Substances:
Year: 2012 PMID: 21951069 DOI: 10.1111/j.1365-2265.2011.04234.x
Source DB: PubMed Journal: Clin Endocrinol (Oxf) ISSN: 0300-0664 Impact factor: 3.478