Ureteral lesions due to endoscopic treatment of vesicoureteral reflux by injection of Teflon: pathological study.

This study, based on the analysis of four samples of terminal ureter obtained at surgical resection, intends to relate the macroscopic and histologic aspect of lesions induced by Teflon injection in the ureteral wall. 6 months after the first injection and 3 months after the second one, the free ureteral lumen is compressed by an intraparietal nodule containing a central area of Teflon spherules and a rim of macrophages and resorptive multi-nucleated giant cells surrounded by a line of connective tissue without a mutilating sclerohyaline reaction. This study, however, is unable to prejudge the long-term future of Teflon or the aspect of the ureteral wall when treatment is efficient.