Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The renin-angiotensin-aldosterone system in 2011: role in hypertension and chronic kidney disease.

Literature DB >> 21947887

The renin-angiotensin-aldosterone system in 2011: role in hypertension and chronic kidney disease.

Ana Cristina Simões E Silva¹, Joseph T Flynn.

Abstract

Over the past two decades, considerable advances have been made in our understanding of the renin-angiotensin-aldosterone system (RAAS) and its roles in various disease states. In this review, we will discuss the current state of knowledge of the many components of the RAAS, including new data on prorenin and its receptors, and important angiotensin fragments. The roles of these components of the RAAS in the pathogenesis of primary hypertension and the progression of chronic kidney disease (CKD) will also be highlighted. Given the new understanding of the many components and roles of the RAAS, it may be possible to develop improved therapies for hypertension and CKD.

Entities: Disease

Mesh：

Substances：
Antihypertensive Agents

Year: 2011 PMID： 21947887 DOI： 10.1007/s00467-011-2002-y

Source DB: PubMed Journal: Pediatr Nephrol ISSN： 0931-041X Impact factor: 3.714

92 in total

1. History about the discovery of the renin-angiotensin system.

Authors: N Basso; N A Terragno
Journal: Hypertension Date: 2001-12-01 Impact factor: 10.190

2. Vasodilator action of angiotensin-(1-7) on isolated rabbit afferent arterioles.

Authors: YiLin Ren; Jeffrey L Garvin; Oscar A Carretero
Journal: Hypertension Date: 2002-03-01 Impact factor: 10.190

3. Angiotensin-(1-7) binds to specific receptors on cardiac fibroblasts to initiate antifibrotic and antitrophic effects.

Authors: Michikado Iwata; Randy T Cowling; Devorah Gurantz; Cristina Moore; Shen Zhang; Jason X-J Yuan; Barry H Greenberg
Journal: Am J Physiol Heart Circ Physiol Date: 2005-07-15 Impact factor: 4.733

4. Angiotensin-(3-7) pressor effect at the rostral ventrolateral medulla.

Authors: Patrícia Maria Ferreira; Robson Augusto Souza Dos Santos; Maria José Campagnole-Santos
Journal: Regul Pept Date: 2007-01-20

5. Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy.

Authors: Carlos M Ferrario; Jasmina Varagic; Javad Habibi; Sayaka Nagata; Johji Kato; Mark C Chappell; Aaron J Trask; Kazuo Kitamura; Adam Whaley-Connell; James R Sowers
Journal: Am J Physiol Heart Circ Physiol Date: 2009-02-13 Impact factor: 4.733

6. Sodium status and angiotensin-converting enzyme inhibition: effects on plasma angiotensin-(1-7) in healthy man.

Authors: Menno J A Kocks; A Titia Lely; Frans Boomsma; Paul E de Jong; Gerjan Navis
Journal: J Hypertens Date: 2005-03 Impact factor: 4.844

7. Increased ACE and decreased ACE2 expression in kidneys from patients with IgA nephropathy.

Authors: Sonoo Mizuiri; Hiromichi Hemmi; Michitsune Arita; Toshiyuki Aoki; Yasushi Ohashi; Moriatsu Miyagi; Ken Sakai; Kazutoshi Shibuya; Hiroki Hase; Atsushi Aikawa
Journal: Nephron Clin Pract Date: 2010-08-04

8. Glomerular localization and expression of Angiotensin-converting enzyme 2 and Angiotensin-converting enzyme: implications for albuminuria in diabetes.

Authors: Minghao Ye; Jan Wysocki; Josette William; Maria José Soler; Ivan Cokic; Daniel Batlle
Journal: J Am Soc Nephrol Date: 2006-10-04 Impact factor: 10.121

9. G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor.

Authors: Evi Kostenis; Graeme Milligan; Arthur Christopoulos; Carlos F Sanchez-Ferrer; Silvia Heringer-Walther; Patrick M Sexton; Florian Gembardt; Elaine Kellett; Lene Martini; Patrick Vanderheyden; Heinz-Peter Schultheiss; Thomas Walther
Journal: Circulation Date: 2005-04-04 Impact factor: 29.690

10. Diuresis and natriuresis produced by long term administration of a selective Angiotensin-(1-7) antagonist in normotensive and hypertensive rats.

Authors: A C Simões e Silva; A P Bello; N C Baracho; M C Khosla; R A Santos
Journal: Regul Pept Date: 1998-06-30

18 in total

1. A role for the circadian clock protein Per1 in the regulation of aldosterone levels and renal Na+ retention.

Authors: Jacob Richards; Kit-Yan Cheng; Sean All; George Skopis; Lauren Jeffers; I Jeanette Lynch; Charles S Wingo; Michelle L Gumz
Journal: Am J Physiol Renal Physiol Date: 2013-10-23

Review 2. ACE2 (Angiotensin-Converting Enzyme 2), COVID-19, and ACE Inhibitor and Ang II (Angiotensin II) Receptor Blocker Use During the Pandemic: The Pediatric Perspective.

Authors: Andrew M South; Tammy M Brady; Joseph T Flynn
Journal: Hypertension Date: 2020-05-05 Impact factor: 10.190

Review 3. The role of the kidney in regulating arterial blood pressure.

Authors: Hani M Wadei; Stephen C Textor
Journal: Nat Rev Nephrol Date: 2012-08-28 Impact factor: 28.314

Review 4. Aliskiren, the first direct renin inhibitor: assessing a role in pediatric hypertension and kidney diseases.

Authors: Shahid Nadeem; Donald L Batisky
Journal: Pediatr Nephrol Date: 2013-12-14 Impact factor: 3.714

Review 5. Stem cells as a therapeutic approach to chronic kidney diseases.

Authors: Sargis Sedrakyan; Susanne Angelow; Roger E De Filippo; Laura Perin
Journal: Curr Urol Rep Date: 2012-02 Impact factor: 3.092

6. Effects of Na/K-ATPase and its ligands on bone marrow stromal cell differentiation.

Authors: Moustafa Sayed; Christopher A Drummond; Kaleigh L Evans; Steven T Haller; Jiang Liu; Zijian Xie; Jiang Tian
Journal: Stem Cell Res Date: 2014-04-13 Impact factor: 2.020

7. Kidney single-cell transcriptome profile reveals distinct response of proximal tubule cells to SGLT2i and ARB treatment in diabetic mice.

Authors: Jinshan Wu; Zeguo Sun; Shumin Yang; Jia Fu; Ying Fan; Niansong Wang; Jinbo Hu; Linqiang Ma; Chuan Peng; Zhihong Wang; Kyung Lee; John Cijiang He; Qifu Li
Journal: Mol Ther Date: 2021-10-19 Impact factor: 12.910