Literature DB >> 21946744

Narcolepsy in New Zealand: pathway to diagnosis and effect on quality of life.

Angela J Campbell1, T Leigh Signal, Karyn M O'Keeffe, Jessie P Bakker.   

Abstract

AIMS: There has been no attempt to survey New Zealanders with narcolepsy to determine their pathway to diagnosis, symptoms, treatment, or quality of life. We therefore aimed to develop a comprehensive questionnaire, and compare responses on measures of daytime sleepiness and quality of life between individuals with narcolepsy and the general New Zealand population.
METHODS: A questionnaire was developed encompassing descriptive information, daytime sleepiness and sleep habits, general health and wellbeing, diagnosis and treatment of narcolepsy, symptoms, and quality of life. Ninety-two individuals were identified through medical specialists and a local support group.
RESULTS: Complete responses were obtained from 54 individuals (63% female, mean age 54.7 ± 18.3 years). The mean Epworth Sleepiness Scale score was 16.4 ± 5.4 (/24). Symptoms first appeared at 20.7 ± 9.7 years of age on average, although diagnosis did not take place until 33.4 ± 13.8 years of age. Individuals with narcolepsy reported substantially lower health-related quality of life than the general New Zealand population. Less than half of those diagnosed with narcolepsy had undergone an objective evaluation including a sleep study.
CONCLUSIONS: New Zealanders with narcolepsy suffer from an excessive level of daytime sleepiness, and have significantly poorer health-related quality of life than the general population. There are a number of inconsistencies between the diagnostic pathway in New Zealand and best-practice guidelines for diagnosis and treatment.

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Year:  2011        PMID: 21946744

Source DB:  PubMed          Journal:  N Z Med J        ISSN: 0028-8446


  8 in total

1.  Medical specialty visits and diagnoses received by Saudi patients prior to a diagnosis of narcolepsy.

Authors:  Aljohara S Almeneessier; Sara Al-Jebrin; Reem Labani; Hussain Alkaff; Omar Al-Rahbeeni; Musab Alageel; Awad Olaish; Ahmed S BaHammam
Journal:  Sleep Breath       Date:  2019-02-28       Impact factor: 2.816

2.  Prevalence, incidence, and health care utilization of patients with narcolepsy: a population-representative study.

Authors:  Ulf Kallweit; Georg Nilius; Daniel Trümper; Tobias Vogelmann; Tino Schubert
Journal:  J Clin Sleep Med       Date:  2022-06-01       Impact factor: 4.324

Review 3.  The Medical and Economic Burden of Narcolepsy: Implications for Managed Care.

Authors:  Michael J Thorpy; George Hiller
Journal:  Am Health Drug Benefits       Date:  2017-07

4.  Delayed diagnosis, range of severity, and multiple sleep comorbidities: a clinical and polysomnographic analysis of 100 patients of the innsbruck narcolepsy cohort.

Authors:  Birgit Frauscher; Laura Ehrmann; Thomas Mitterling; David Gabelia; Viola Gschliesser; Elisabeth Brandauer; Werner Poewe; Birgit Högl
Journal:  J Clin Sleep Med       Date:  2013-08-15       Impact factor: 4.062

5.  Evaluation of Quality of Life in Patients With Narcolepsy Treated With Sodium Oxybate: Use of the 36-Item Short-Form Health Survey in a Clinical Trial.

Authors:  Richard Bogan; Todd Swick; Mortimer Mamelak; Ruzica Kovacevic-Ristanovic; Chinglin Lai; Jed Black; Kathleen F Villa; Jacques Montplaisir
Journal:  Neurol Ther       Date:  2016-10-24

6.  Correlation of Changes in Patient-Reported Quality of Life With Physician-Rated Global Impression of Change in Patients With Narcolepsy Participating in a Clinical Trial of Sodium Oxybate: A Post Hoc Analysis.

Authors:  Richard K Bogan; Jed Black; Todd Swick; Mortimer Mamelak; Ruzica Kovacevic-Ristanovic; Kathleen F Villa; Fannie Mori; Jacques Montplaisir
Journal:  Neurol Ther       Date:  2017-07-13

7.  Spectral Analysis of Polysomnography in Narcolepsy.

Authors:  Seok Ho Yun; Ho Dong Choi; Wan Seok Seo
Journal:  Psychiatry Investig       Date:  2017-03-06       Impact factor: 2.505

8.  Central Disorders of Hypersomnolence in Children and Adults: A Comparative Study from South India.

Authors:  Madhukar Trivedi; Sapna Erat Sreedharan; Shana N Nair; C A Anees; J P Unnikrishnan; P S Sarma; Ashalatha Radhakrishnan
Journal:  Ann Indian Acad Neurol       Date:  2019-10-25       Impact factor: 1.383

  8 in total

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