PURPOSE: Using MicroPerimetry MP-1 to assess the fixation behavior in early and moderate primary open angle glaucoma (POAG). METHODS: Thirty-nine early and moderate POAG eyes and 22 normal eyes were enrolled prospectively. The stability and location of the fixation in each subject eye were recorded by the macula 10-degree program of the microperimeter (MP-1). Retinal sensitivity was examined using the G2 program phase 1 of an Octopus 101 perimeter and the macula 10-degree program of the MP-1. The fixation behavior and the retinal sensitivity were compared between POAG and control groups. The correlation between the fixation behavior and the retinal sensitivity was analyzed in POAG patients. RESULTS: : Fixation instability was detected in POAG (P=0.016). It correlated with the mean defect on Octopus perimeter and all the mean macular sensitivity parameters of MP-1, which includes the central 10 degrees (r=0.416, P=0.008), 6 degrees (r=0.401, P=0.011), 2 degrees (r=0.376, P=0.018), inferotemporal (r=0.399, P=0.012) and inferonasal (r=0.387, P=0.015) quadrants of the central 6 degrees. All the POAG patients had a predominantly central fixation. CONCLUSION: Fixation instability manifested in early and moderate POAG eyes, which may be an early sign of POAG.
PURPOSE: Using MicroPerimetry MP-1 to assess the fixation behavior in early and moderate primary open angle glaucoma (POAG). METHODS: Thirty-nine early and moderate POAG eyes and 22 normal eyes were enrolled prospectively. The stability and location of the fixation in each subject eye were recorded by the macula 10-degree program of the microperimeter (MP-1). Retinal sensitivity was examined using the G2 program phase 1 of an Octopus 101 perimeter and the macula 10-degree program of the MP-1. The fixation behavior and the retinal sensitivity were compared between POAG and control groups. The correlation between the fixation behavior and the retinal sensitivity was analyzed in POAG patients. RESULTS: : Fixation instability was detected in POAG (P=0.016). It correlated with the mean defect on Octopus perimeter and all the mean macular sensitivity parameters of MP-1, which includes the central 10 degrees (r=0.416, P=0.008), 6 degrees (r=0.401, P=0.011), 2 degrees (r=0.376, P=0.018), inferotemporal (r=0.399, P=0.012) and inferonasal (r=0.387, P=0.015) quadrants of the central 6 degrees. All the POAG patients had a predominantly central fixation. CONCLUSION: Fixation instability manifested in early and moderate POAG eyes, which may be an early sign of POAG.
Authors: Luca Scuderi; Irene Gattazzo; Alessandro de Paula; Clemente Maria Iodice; Federico Di Tizio; Andrea Perdicchi Journal: Int Ophthalmol Date: 2022-01-30 Impact factor: 2.029
Authors: Galia Issashar Leibovitzh; Graham E Trope; Yvonne M Buys; Luminita Tarita-Nistor Journal: Front Aging Neurosci Date: 2022-05-25 Impact factor: 5.702
Authors: Luca Rossetti; Maurizio Digiuni; Alberto Rosso; Roberta Riva; Giuliano Barbaro; Michael K Smolek; Nicola Orzalesi; Stefano De Cilla'; Alessandro Autelitano; Paolo Fogagnolo Journal: PLoS One Date: 2015-03-25 Impact factor: 3.240
Authors: Giovanni Montesano; Luca M Rossetti; Davide Allegrini; Mario R Romano; David F Garway-Heath; David P Crabb Journal: Transl Vis Sci Technol Date: 2021-02-05 Impact factor: 3.283
Authors: Giovanni Montesano; David P Crabb; Pete R Jones; Paolo Fogagnolo; Maurizio Digiuni; Luca M Rossetti Journal: BMC Ophthalmol Date: 2018-08-03 Impact factor: 2.209