STUDY OBJECTIVE: To treat heterotopic pregnancy with a minimally invasive procedure, absent a feticide drug. DESIGN: Retrospective study (Canadian Classification III). SETTING: University-affiliated hospital, center of reproductive medicine, department of obstetrics and gynecology, central south university, Changsha Hunan China. PATIENTS: A total of nine patients' diagnosed cornual heterotopic pregnancy resulted from assisted reproduction technology. Among nine, five patients selected the cornual embryo reduction. INTERVENTIONS: Cornual embryo reduction and preservation of intrauterine embryo were done under guidance of transvaginal ultrasonography at 4-6 weeks after embryo transfer. No drug was given. MEASUREMENTS: Safety of operative procedure and pregnancy outcome. MAIN RESULTS: All five patients who underwent selective embryo reduction has no intraoperative or postoperative complication, however 3 of them delivered healthy babies while two aborted. CONCLUSION: An early intervention should be carried in vital stable patients by means of puncturing and aspirating cornual heterotopic pregnancy under transvaginal ultrasound guidance.
STUDY OBJECTIVE: To treat heterotopic pregnancy with a minimally invasive procedure, absent a feticide drug. DESIGN: Retrospective study (Canadian Classification III). SETTING: University-affiliated hospital, center of reproductive medicine, department of obstetrics and gynecology, central south university, Changsha Hunan China. PATIENTS: A total of nine patients' diagnosed cornual heterotopic pregnancy resulted from assisted reproduction technology. Among nine, five patients selected the cornual embryo reduction. INTERVENTIONS: Cornual embryo reduction and preservation of intrauterine embryo were done under guidance of transvaginal ultrasonography at 4-6 weeks after embryo transfer. No drug was given. MEASUREMENTS: Safety of operative procedure and pregnancy outcome. MAIN RESULTS: All five patients who underwent selective embryo reduction has no intraoperative or postoperative complication, however 3 of them delivered healthy babies while two aborted. CONCLUSION: An early intervention should be carried in vital stable patients by means of puncturing and aspirating cornual heterotopic pregnancy under transvaginal ultrasound guidance.