OBJECTIVE: To evaluate whether hysteroscopic septoplasty should be performed in all women diagnosed with subseptate uterus. METHODS: In a prospective study, 138 patients diagnosed with subseptate uterus at the First Affiliated Hospital of Guangxi Medical University, Nanning, China, were enrolled between January 1, 2006, and March 1, 2011, and reproductive outcomes were compared among women who did and those who did not undergo hysteroscopic resection. Women were divided in 2 groups: group A comprised women with a history of recurrent spontaneous abortion (RSA), and was subdivided into control (A1) and surgery (A2) groups; group B comprised women with no history of poor reproductive outcomes, and was subdivided into control (B1) and surgery (B2) groups. RESULTS: The rates of pregnancy and term delivery were higher in group A2 than in group A1 (P<0.05). The incidence of RSA and preterm delivery was higher in group A1 than in group A2 (P<0.05). There was no difference in pregnancy rate, incidence of RSA, or preterm or term delivery between group B1 and group B2. CONCLUSION:Hysteroscopic septoplasty significantly improved pregnancy outcomes in women with a history of RSA, but did not influence reproductive outcomes in women with no history of poor pregnancy outcomes.
RCT Entities:
OBJECTIVE: To evaluate whether hysteroscopic septoplasty should be performed in all women diagnosed with subseptate uterus. METHODS: In a prospective study, 138 patients diagnosed with subseptate uterus at the First Affiliated Hospital of Guangxi Medical University, Nanning, China, were enrolled between January 1, 2006, and March 1, 2011, and reproductive outcomes were compared among women who did and those who did not undergo hysteroscopic resection. Women were divided in 2 groups: group A comprised women with a history of recurrent spontaneous abortion (RSA), and was subdivided into control (A1) and surgery (A2) groups; group B comprised women with no history of poor reproductive outcomes, and was subdivided into control (B1) and surgery (B2) groups. RESULTS: The rates of pregnancy and term delivery were higher in group A2 than in group A1 (P<0.05). The incidence of RSA and preterm delivery was higher in group A1 than in group A2 (P<0.05). There was no difference in pregnancy rate, incidence of RSA, or preterm or term delivery between group B1 and group B2. CONCLUSION: Hysteroscopic septoplasty significantly improved pregnancy outcomes in women with a history of RSA, but did not influence reproductive outcomes in women with no history of poor pregnancy outcomes.
Authors: Marco Noventa; Giulia Spagnol; Matteo Marchetti; Carlo Saccardi; Giulio Bonaldo; Antonio Simone Laganà; Francesco Cavallin; Alessandra Andrisani; Guido Ambrosini; Salvatore Giovanni Vitale; Luis Alonso Pacheco; Sergio Haimovich; Attilio Di Spiezio Sardo; Jose Carugno; Marco Scioscia; Simone Garzon; Stefano Bettocchi; Giovanni Buzzaccarini; Roberto Tozzi; Amerigo Vitagliano Journal: J Clin Med Date: 2022-06-08 Impact factor: 4.964
Authors: J F W Rikken; K W J Verhorstert; M H Emanuel; M Y Bongers; T Spinder; W K H Kuchenbecker; F W Jansen; J W van der Steeg; C A H Janssen; K Kapiteijn; W A Schols; B Torrenga; H L Torrance; H R Verhoeve; J A F Huirne; A Hoek; T E Nieboer; I A J van Rooij; T J Clark; L Robinson; M D Stephenson; B W J Mol; F van der Veen; M van Wely; M Goddijn Journal: Hum Reprod Date: 2020-07-01 Impact factor: 6.918
Authors: J F W Rikken; C R Kowalik; M H Emanuel; M Y Bongers; T Spinder; J H de Kruif; K W M Bloemenkamp; F W Jansen; S Veersema; A G M G J Mulders; A L Thurkow; K Hald; A Mohazzab; Y Khalaf; T J Clark; M Farrugia; H A van Vliet; M S Stephenson; F van der Veen; M van Wely; B W J Mol; M Goddijn Journal: BMC Womens Health Date: 2018-10-05 Impact factor: 2.809