Literature DB >> 21944794

Simplified minimally invasive parathyroidectomy: a series of 100 cases and review of the literature.

W Wong1, F J Foo, M I Lau, A Sarin, P Kiruparan.   

Abstract

INTRODUCTION: Conventional practice of parathyroidectomy has been collar incision with bilateral neck exploration and a four-gland evaluation. Our local practice involves simplified parathyroidectomy via mini-incision without routine use of intraoperative adjuncts. The aim of this study is to demonstrate that a good success rate can be achieved, which will hopefully encourage more to undertake minimally invasive parathyroid surgery.
MATERIALS AND METHODS: A prospective case series of the first 100 patients undergoing minimally invasive parathyroidectomy (MIP) by a single surgeon at a single institution were included. Preoperatively, patients underwent ultrasonography (US) and/or a sestamibi (MIBI) scan for localisation. Parathyroidectomy was performed following an algorithm of intraoperative decisions. Serum calcium and/or parathyroid hormone levels were checked at follow-up. Postoperative normocalcaemia was considered success independent of serum parathyroid hormone levels
RESULTS: The patients had a median age of 63 years. Of the 100 patients, 83 were female and 17 male. Seven patients had a conversion to bilateral exploration. The mean operative time for unilateral and bilateral exploration was 42.38 minutes and 76.43 minutes respectively. Separately, a MIBI scan and US lateralised the side of the lesion in 82.8% and 79.5% of cases respectively. When US and the MIBI scan agreed, the predictive accuracy of the side of the lesion was 87.5%. The majority of patients (96%) had a successful return to normocalcaemia. No complications were encountered.
CONCLUSIONS: Excellent results are achievable with simplified MIP even without intraoperative adjuncts. Preoperative localisation is helpful in determining the side of incision. Our technique demonstrates a key principle of surgery: to keep things simple.

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Year:  2011        PMID: 21944794      PMCID: PMC3363078          DOI: 10.1308/003588411X571836

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  36 in total

1.  Intraoperative parathyroid hormone monitoring fails to detect double parathyroid adenomas: a 2-institution experience.

Authors:  P G Gauger; G Agarwal; B G England; L W Delbridge; K A Matz; M Wilkinson; B G Robinson; N W Thompson
Journal:  Surgery       Date:  2001-12       Impact factor: 3.982

2.  Unilateral versus bilateral neck exploration for primary hyperparathyroidism: a prospective randomized controlled trial.

Authors:  Anders Bergenfelz; Pia Lindblom; Sten Tibblin; Johan Westerdahl
Journal:  Ann Surg       Date:  2002-11       Impact factor: 12.969

3.  [Minimally-invasive parathyroidectomy: a good operative procedure for primary hyperparathyroidism even without the use of intraoperative parathyroid-hormone assessment or a gamma probe].

Authors:  S P Fuchs; A B Smits; P de Hooge; A F Muller; J P Gelissen; Th van Dalen
Journal:  Ned Tijdschr Geneeskd       Date:  2005-06-25

4.  Two hundred consecutive parathyroid ultrasound studies by a single clinician: the impact of experience.

Authors:  Michael W Yeh; Beverley M Barraclough; Stan B Sidhu; Mark S Sywak; Bruce H Barraclough; Leigh W Delbridge
Journal:  Endocr Pract       Date:  2006 May-Jun       Impact factor: 3.443

5.  One hundred consecutive minimally invasive parathyroid explorations.

Authors:  R Udelsman; P I Donovan; L J Sokoll
Journal:  Ann Surg       Date:  2000-09       Impact factor: 12.969

6.  Determinants of Tc-99m sestamibi SPECT scan sensitivity in primary hyperparathyroidism.

Authors:  Todd W Swanson; Simon K Chan; Steven J Jones; Samuel Bugis; Robert Irvine; Allan Belzberg; Daniel Levine; Sam M Wiseman
Journal:  Am J Surg       Date:  2010-05       Impact factor: 2.565

7.  A 10-year prospective study of primary hyperparathyroidism with or without parathyroid surgery.

Authors:  S J Silverberg; E Shane; T P Jacobs; E Siris; J P Bilezikian
Journal:  N Engl J Med       Date:  1999-10-21       Impact factor: 91.245

8.  Minimally invasive parathyroidectomy without intraoperative parathyroid hormone monitoring in patients with primary hyperparathyroidism.

Authors:  R Mihai; F F Palazzo; F V Gleeson; G P Sadler
Journal:  Br J Surg       Date:  2007-01       Impact factor: 6.939

9.  Surgical management of primary hyperparathyroidism - results of a national survey.

Authors:  S Ozbas; S Pain; T Tang; G C Wishart
Journal:  Ann R Coll Surg Engl       Date:  2003-07       Impact factor: 1.891

10.  Asymptomatic primary hyperparathyroidism.

Authors:  B H Mitlak; M Daly; J T Potts; D Schoenfeld; R M Neer
Journal:  J Bone Miner Res       Date:  1991-10       Impact factor: 6.741

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  9 in total

1.  A 20-year study on 190 patients with primary hyperparathyroidism in a developing country: Turkey experience.

Authors:  Arif Usta; Etem Alhan; Akif Cinel; Serdar Türkyılmaz; Cihangir Erem
Journal:  Int Surg       Date:  2015-04

2.  Ultrasonography alone can reliably locate parathyroid tumours and facilitates minimally invasive parathyroidectomy.

Authors:  H Z Butt; M A Husainy; A Bolia; N J M London
Journal:  Ann R Coll Surg Engl       Date:  2015-08-14       Impact factor: 1.891

3.  Open mini-incision parathyroidectomy for solitary parathyroid adenoma: surgical limitations.

Authors:  Oktay Irkorucu; Kamuran Cumhur Değer; Enver Reyan; Ersoy Arslan
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-06-28       Impact factor: 2.503

Review 4.  Updates in primary hyperparathyroidism.

Authors:  Guido Gasparri
Journal:  Updates Surg       Date:  2017-06-23

5.  Management of thyroid nodules incidentally discovered on MIBI scanning for primary hyperparathyroidism.

Authors:  Tristan Greilsamer; Claire Blanchard; Niki Christou; Delphine Drui; Catherine Ansquer; Maelle Le Bras; Bertrand Cariou; Cécile Caillard; Emmanuelle Mourrain-Langlois; Anne Sophie Delemazure; Muriel Mathonnet; Françoise Kraeber-Bodéré; Eric Mirallié
Journal:  Langenbecks Arch Surg       Date:  2015-02-20       Impact factor: 3.445

Review 6.  Outcomes of Parathyroidectomy in Patients with Primary Hyperparathyroidism: A Systematic Review and Meta-analysis.

Authors:  Naykky M Singh Ospina; Rene Rodriguez-Gutierrez; Spyridoula Maraka; Ana E Espinosa de Ycaza; Sina Jasim; Ana Castaneda-Guarderas; Michael R Gionfriddo; Alaa Al Nofal; Juan P Brito; Patricia Erwin; Melanie Richards; Robert Wermers; Victor M Montori
Journal:  World J Surg       Date:  2016-10       Impact factor: 3.352

7.  Robotic-assisted parathyroidectomy via transaxillary approach: feasibility and learning curves.

Authors:  Emad Kandil; Deena Hadedeya; Mahmoud Shalaby; Eman Toraih; David Aparício; Meghan Garstka; Ruhul Munshi; Ahmed Elnahla; Jonathon O Russell; Patrick Aidan
Journal:  Gland Surg       Date:  2021-03

8.  Clinical usefulness of intraoperative parathyroid hormone monitoring for primary hyperparathyroidism.

Authors:  Se Hyun Paek; Su-Jin Kim; June Young Choi; Kyu Eun Lee
Journal:  Ann Surg Treat Res       Date:  2018-01-30       Impact factor: 1.859

9.  Focused parathyroidectomy for single parathyroid adenoma: a clinical account of 20 patients.

Authors:  Hany Abdelfatah El-Hady; Hisham Saleh Radwan
Journal:  Electron Physician       Date:  2018-06-25
  9 in total

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