Literature DB >> 2194197

Sustained-release delivery systems for treatment of dental diseases.

M Friedman1, D Steinberg.   

Abstract

Sustained-release delivery systems allow the effective targeting of drugs for treating dental and periodontal diseases. Since dental diseases are chronic, the therapeutic agents used should persist in the oral cavity for as long as possible. Implanting fluoride, chlorhexidine, and other antiseptic agents embedded into sustained-release polymeric matrices into the oral cavity prevents cariogenic plaque accumulation. Both fibers and slab-like sustained-delivery devices bearing chemotherapeutic agents reduced periopathogenic bacteria levels associated with clinical improvement. This review provides useful background information for researchers seeking to develop controlled-release delivery systems for dental applications.

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Year:  1990        PMID： 2194197     DOI： 10.1023/a:1015898717936

Source DB:  PubMed          Journal:  Pharm Res        ISSN： 0724-8741            Impact factor:   4.200


  35 in total

1.  Epidemiology of dental disease.

Authors:  D E Barmes
Journal:  J Clin Periodontol       Date:  1977-12       Impact factor: 8.728

2.  Clinical and microbiological effects of sustained release chlorhexidine in periodontal pockets.

Authors:  A Stabholz; M N Sela; M Friedman; G Golomb; A Soskolne
Journal:  J Clin Periodontol       Date:  1986-09       Impact factor: 8.728

3.  The effect of local application of a sustained release delivery system of chlorhexidine on plaque accumulation.

Authors:  L Brayer; Z Schwartz; A Stabholtz; H Schibli; M Friedman
Journal:  Clin Prev Dent       Date:  1988 Jan-Feb

4.  Plaque inhibition by sustained release of chlorhexidine from removable appliances.

Authors:  M Friedman; D Harari; H Raz; G Golomb; L Brayer
Journal:  J Dent Res       Date:  1985-11       Impact factor: 6.116

5.  A 4-month study on the effect of chlorhexidine mouth washes on 50 soldiers.

Authors:  L Flötra; P Gjermo; G Rölla; J Waerhaug
Journal:  Scand J Dent Res       Date:  1972

6.  Microbiological and clinical short-term effects of repeated intracrevicular chlorhexidine rinsings.

Authors:  M Westling; G Tynelius-Bratthall
Journal:  J Periodontal Res       Date:  1984-03       Impact factor: 4.419

7.  Experimental use of a slow release device employing chlorhexidine gluconate in areas of acute periodontal inflammation.

Authors:  J Coventry; H N Newman
Journal:  J Clin Periodontol       Date:  1982-03       Impact factor: 8.728

8.  New sustained release dosage form of chlorhexidine for dental use: use for plaque control in partial denture wearers.

Authors:  Z Hirschfeld; M Friedman; G Golomb; D Ben-Yaacov
Journal:  J Oral Rehabil       Date:  1984-09       Impact factor: 3.837

9.  Periodontal therapy by local delivery of tetracycline.

Authors:  J M Goodson; A Haffajee; S S Socransky
Journal:  J Clin Periodontol       Date:  1979-04       Impact factor: 8.728

10.  Slow release metronidazole and a simplified mechanical oral hygiene regimen in the control of chronic periodontitis.

Authors:  H N Newman; F I Yeung; W Z wan Yusof; M Addy
Journal:  J Clin Periodontol       Date:  1984-10       Impact factor: 8.728
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  8 in total

1.  Development of a system to adsorb drugs onto calcium phosphate materials.

Authors:  A C Queiroz; J D Santos; F J Monteiro
Journal:  J Mater Sci Mater Med       Date:  2005-07       Impact factor: 3.896

2.  Sustained release of a novel anti-quorum-sensing agent against oral fungal biofilms.

Authors:  Mark Feldman; Julia Shenderovich; Abed Al Aziz Al-Quntar; Michael Friedman; Doron Steinberg
Journal:  Antimicrob Agents Chemother       Date:  2015-02-02       Impact factor: 5.191

Review 3.  The unusual routes of administration.

Authors:  E Beyssac
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1996 Apr-Jun       Impact factor: 2.441

4.  Comparison of the efficacy of a novel sustained release clotrimazole varnish and clotrimazole troches for the treatment of oral candidiasis.

Authors:  Rakefet Czerninski; Anna Pikovsky; Irith Gati; Michael Friedman; Doron Steinberg
Journal:  Clin Oral Investig       Date:  2014-05-28       Impact factor: 3.573

5.  Fluoride and chlorhexidine release from filled resins.

Authors:  C Shen; N-Z Zhang; K J Anusavice
Journal:  J Dent Res       Date:  2010-06-25       Impact factor: 6.116

Review 6.  Bone as an effect compartment : models for uptake and release of drugs.

Authors:  David Stepensky; Lilach Kleinberg; Amnon Hoffman
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

7.  A novel sustained-release clotrimazole varnish for local treatment of oral candidiasis.

Authors:  Rakefet Czerninski; Sagi Sivan; Doron Steinberg; Irith Gati; Leonid Kagan; Michael Friedman
Journal:  Clin Oral Investig       Date:  2009-04-29       Impact factor: 3.573

8.  Potential Combinatory Effect of Cannabidiol and Triclosan Incorporated into Sustained Release Delivery System against Oral Candidiasis.

Authors:  Mark Feldman; Irith Gati; Ronit Vogt Sionov; Sharonit Sahar-Helft; Michael Friedman; Doron Steinberg
Journal:  Pharmaceutics       Date:  2022-08-03       Impact factor: 6.525
  8 in total

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