Literature DB >> 21940476

Molecular epidemiology of Clostridium difficile strains in children compared with that of strains circulating in adults with Clostridium difficile-associated infection.

Nicole Stoesser1, Derrick W Crook, Rowena Fung, David Griffiths, Rosalind M Harding, Melina Kachrimanidou, Satish Keshav, Tim E Peto, Alison Vaughan, A Sarah Walker, Kate E Dingle.   

Abstract

Molecular analysis of Clostridium difficile (28 isolates) from children (n = 128) in Oxfordshire, United Kingdom, identified eight toxigenic genotypes. Six of these were isolated from 27% of concurrent adult C. difficile-associated infections studied (n = 83). No children carried hypervirulent PCR ribotype 027. Children could participate in the transmission of some adult disease-causing genotypes.

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Year:  2011        PMID: 21940476      PMCID: PMC3209104          DOI: 10.1128/JCM.05349-11

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  22 in total

1.  Clostridium difficile in neonates: serogrouping and epidemiology.

Authors:  M Delmée; G Verellen; V Avesani; G Francois
Journal:  Eur J Pediatr       Date:  1988-01       Impact factor: 3.183

2.  The role of Clostridium difficile and viruses as causes of nosocomial diarrhea in children.

Authors:  Joanne M Langley; John C LeBlanc; Martha Hanakowski; Olga Goloubeva
Journal:  Infect Control Hosp Epidemiol       Date:  2002-11       Impact factor: 3.254

3.  Definition of the single integration site of the pathogenicity locus in Clostridium difficile.

Authors:  V Braun; T Hundsberger; P Leukel; M Sauerborn; C von Eichel-Streiber
Journal:  Gene       Date:  1996-11-28       Impact factor: 3.688

4.  Prevalence and diversity of Clostridium difficile strains in infants.

Authors:  Clotilde Rousseau; Ludovic Lemée; Alban Le Monnier; Isabelle Poilane; Jean-Louis Pons; Anne Collignon
Journal:  J Med Microbiol       Date:  2011-03-10       Impact factor: 2.472

5.  Recovery of Clostridium difficile from children.

Authors:  E Holst; I Helin; P A Mårdh
Journal:  Scand J Infect Dis       Date:  1981

6.  Colonization of the large bowel by Clostridium difficile in healthy infants: quantitative study.

Authors:  P L Stark; A Lee; B D Parsonage
Journal:  Infect Immun       Date:  1982-03       Impact factor: 3.441

7.  Clostridium difficile cytotoxin in a pediatric population.

Authors:  C M Thompson; P H Gilligan; M C Fisher; S S Long
Journal:  Am J Dis Child       Date:  1983-03

8.  Asymptomatic neonatal colonisation by Clostridium difficile.

Authors:  R P Bolton; S K Tait; P R Dear; M S Losowsky
Journal:  Arch Dis Child       Date:  1984-05       Impact factor: 3.791

9.  Presence of the epidemic North American Pulsed Field type 1 Clostridium difficile strain in hospitalized children.

Authors:  Philip Toltzis; Jason Kim; Michael Dul; Joan Zoltanski; Sarah Smathers; Theoklis Zaoutis
Journal:  J Pediatr       Date:  2009-04       Impact factor: 4.406

10.  A case-control study of community-associated Clostridium difficile infection.

Authors:  M H Wilcox; L Mooney; R Bendall; C D Settle; W N Fawley
Journal:  J Antimicrob Chemother       Date:  2008-04-22       Impact factor: 5.790

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  18 in total

1.  Differences in the Molecular Epidemiology and Antibiotic Susceptibility of Clostridium difficile Isolates in Pediatric and Adult Patients.

Authors:  Larry K Kociolek; Dale N Gerding; James R Osmolski; Sameer J Patel; David R Snydman; Laura A McDermott; David W Hecht
Journal:  Antimicrob Agents Chemother       Date:  2016-07-22       Impact factor: 5.191

2.  Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA).

Authors:  L Clifford McDonald; Dale N Gerding; Stuart Johnson; Johan S Bakken; Karen C Carroll; Susan E Coffin; Erik R Dubberke; Kevin W Garey; Carolyn V Gould; Ciaran Kelly; Vivian Loo; Julia Shaklee Sammons; Thomas J Sandora; Mark H Wilcox
Journal:  Clin Infect Dis       Date:  2018-03-19       Impact factor: 9.079

3.  Reducing C. difficile in children: An agent-based modeling approach to evaluate intervention effectiveness.

Authors:  Anna K Barker; Elizabeth Scaria; Oguzhan Alagoz; Ajay K Sethi; Nasia Safdar
Journal:  Infect Control Hosp Epidemiol       Date:  2020-02-13       Impact factor: 3.254

4.  Clostridium difficile as a cause of healthcare-associated diarrhoea among children in Auckland, New Zealand: clinical and molecular epidemiology.

Authors:  V Sathyendran; G N McAuliffe; T Swager; J T Freeman; S L Taylor; S A Roberts
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-05-09       Impact factor: 3.267

Review 5.  Understanding Clostridium difficile Colonization.

Authors:  Monique J T Crobach; Jonathan J Vernon; Vivian G Loo; Ling Yuan Kong; Séverine Péchiné; Mark H Wilcox; Ed J Kuijper
Journal:  Clin Microbiol Rev       Date:  2018-03-14       Impact factor: 26.132

Review 6.  Clostridium difficile infection: epidemiology, diagnosis and understanding transmission.

Authors:  Jessica S H Martin; Tanya M Monaghan; Mark H Wilcox
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2016-03-09       Impact factor: 46.802

Review 7.  Comparison of pediatric and adult antibiotic-associated diarrhea and Clostridium difficile infections.

Authors:  Lynne Vernice McFarland; Metehan Ozen; Ener Cagri Dinleyici; Shan Goh
Journal:  World J Gastroenterol       Date:  2016-03-21       Impact factor: 5.742

8.  Evolutionary history of the Clostridium difficile pathogenicity locus.

Authors:  Kate E Dingle; Briony Elliott; Esther Robinson; David Griffiths; David W Eyre; Nicole Stoesser; Alison Vaughan; Tanya Golubchik; Warren N Fawley; Mark H Wilcox; Timothy E Peto; A Sarah Walker; Thomas V Riley; Derrick W Crook; Xavier Didelot
Journal:  Genome Biol Evol       Date:  2014-01       Impact factor: 3.416

9.  Susceptibility of hamsters to Clostridium difficile isolates of differing toxinotype.

Authors:  Anthony M Buckley; Janice Spencer; Lindsay M Maclellan; Denise Candlish; June J Irvine; Gillian R Douce
Journal:  PLoS One       Date:  2013-05-21       Impact factor: 3.240

Review 10.  Community-acquired Clostridium difficile infection: an increasing public health threat.

Authors:  Arjun Gupta; Sahil Khanna
Journal:  Infect Drug Resist       Date:  2014-03-17       Impact factor: 4.003

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