Literature DB >> 21939394

Variability in the treatment of acute spinal cord injury in the United Kingdom: results of a national survey.

Melissa C Werndle1, Argyro Zoumprouli, Philip Sedgwick, Marios C Papadopoulos.   

Abstract

The aim of this study was to examine how traumatic spinal cord injury is managed in the United Kingdom via a questionnaire survey of all neurosurgical units. We contacted consultant neurosurgeons and neuroanesthetists in all neurosurgical centers that manage patients with acute spinal cord injury. Two clinical scenarios-of complete and incomplete cervical spinal cord injuries-were given to determine local treatment policies. There were 175 responders from the 33 centers (36% response rate). We ascertained neurosurgical views on urgency of transfer, timing of surgery, nature and aim of surgery, as well as neuroanesthetic views on type of anesthetic, essential intraoperative monitoring, drug treatment, and intensive care management. Approximately 70% of neurosurgeons will admit patients with incomplete spinal cord injury immediately, but only 40% will admit patients with complete spinal cord injury immediately. There is no consensus on the timing or even the role of surgery for incomplete or complete injuries. Most (96%) neuroanesthetists avoid anesthetics known to elevate intracranial pressure. What was deemed essential intraoperative monitoring, however, varied widely. Many (22%) neuroanesthetists do not routinely measure arterial blood pressure invasively, central venous pressure (85%), or cardiac output (94%) during surgery. There is no consensus among neuroanesthetists on the optimal levels of arterial blood pressure, or oxygen and carbon dioxide partial arterial pressure. We report wide variability among U.K. neurosurgeons and neuroanesthetists in their treatment of acute traumatic spinal cord injury. Our findings reflect the lack of Class 1 evidence that early surgical decompression and intensive medical management of patients with spinal cord injury improves neurological outcome.

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Year:  2011        PMID: 21939394     DOI: 10.1089/neu.2011.2038

Source DB:  PubMed          Journal:  J Neurotrauma        ISSN: 0897-7151            Impact factor:   5.269


  19 in total

1.  Preferences of adults with spinal cord injury for widely used health-related quality of life and subjective well-being measures.

Authors:  Alina Ionela Palimaru; William E Cunningham; Marcus Dillistone; Arturo Vargas-Bustamante; Honghu Liu; Ron D Hays
Journal:  J Spinal Cord Med       Date:  2018-05-23       Impact factor: 1.985

2.  A comparison of perceptions of quality of life among adults with spinal cord injury in the United States versus the United Kingdom.

Authors:  Alina Palimaru; William E Cunningham; Marcus Dillistone; Arturo Vargas-Bustamante; Honghu Liu; Ron D Hays
Journal:  Qual Life Res       Date:  2017-07-15       Impact factor: 4.147

Review 3.  Knowledge translation and implementation in spinal cord injury: a systematic review.

Authors:  V K Noonan; D L Wolfe; N P Thorogood; S E Park; J T Hsieh; J J Eng
Journal:  Spinal Cord       Date:  2014-05-06       Impact factor: 2.772

4.  Timing of surgery in traumatic spinal cord injury: a national, multidisciplinary survey.

Authors:  P V Ter Wengel; R E Feller; A Stadhouder; D Verbaan; F C Oner; J C Goslings; W P Vandertop
Journal:  Eur Spine J       Date:  2018-03-23       Impact factor: 3.134

5.  Intraspinal Pressure Monitoring in a Patient with Spinal Cord Injury Reveals Different Intradural Compartments: Injured Spinal Cord Pressure Evaluation (ISCoPE) Study.

Authors:  Isaac Phang; Marios C Papadopoulos
Journal:  Neurocrit Care       Date:  2015-12       Impact factor: 3.210

Review 6.  A review of spinal cord perfusion pressure guided interventions in traumatic spinal cord injury.

Authors:  Mathias Møller Thygesen; Tim Damgaard Nielsen; Mads Rasmussen; Dariusz Orlowski; Michael Pedersen; Mikkel Mylius Rasmussen
Journal:  Eur Spine J       Date:  2021-06-25       Impact factor: 3.134

7.  Current use of methylprednisolone for acute spinal cord injury in Poland: survey study.

Authors:  Grzegorz Miekisiak; Wojciech Kloc; Witold Janusz; Jacek Kaczmarczyk; Dariusz Latka; Daniel Zarzycki
Journal:  Eur J Orthop Surg Traumatol       Date:  2014-02-05

8.  Wogonoside alleviates inflammation induced by traumatic spinal cord injury by suppressing NF-κB and NLRP3 inflammasome activation.

Authors:  Yonglin Zhu; Hanzhong Zhu; Zhaojie Wang; Fengguang Gao; Jingsheng Wang; Wenqiang Zhang
Journal:  Exp Ther Med       Date:  2017-08-08       Impact factor: 2.447

9.  Incidence of acute spinal cord injury and associated complications of methylprednisolone therapy: a national population-based study in South Korea.

Authors:  Sung Hoon Choi; Chang-Ho Sung; Dong Ryul Heo; Soo-Young Jeong; Chang-Nam Kang
Journal:  Spinal Cord       Date:  2019-09-16       Impact factor: 2.772

10.  Expansion duroplasty improves intraspinal pressure, spinal cord perfusion pressure, and vascular pressure reactivity index in patients with traumatic spinal cord injury: injured spinal cord pressure evaluation study.

Authors:  Isaac Phang; Melissa C Werndle; Samira Saadoun; Georgios Varsos; Marek Czosnyka; Argyro Zoumprouli; Marios C Papadopoulos
Journal:  J Neurotrauma       Date:  2015-05-04       Impact factor: 5.269

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