| Literature DB >> 21939196 |
Emma-Claire Elliott1, Elizabeth R Bowkett, James L Maggs, John Bacsa, B Kevin Park, Sophie L Regan, Paul M O'Neill, Andrew V Stachulski.
Abstract
Efficient procedures for the synthesis of benzo-fluorinated dibenz[b,f]azepines (iminostilbenes) from fluorinated isatins or indoles using a number of ring-expansion reactions are described. A range of mono- and difluorinated analogues is accessible, and the syntheses can deliver gram quantities of the final products, which are precursors of fluoro analogues of the important anticonvulsant carbamazepine.Entities:
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Year: 2011 PMID： 21939196 DOI： 10.1021/ol202318w
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005