Literature DB >> 21936796

Lipidomics of polyunsaturated-fatty-acid-derived oxygenated metabolites.

Karen A Massey1, Anna Nicolaou.   

Abstract

Nutritionally important PUFAs (polyunsaturated fatty acids) mediate some of their bioactivities through formation of oxygenated metabolites. These bioactive lipids are formed by COX (cyclo-oxygenase), LOX (lipoxygenase) and cytochrome-P450-catalysed reactions, as well as non-enzymatic lipid peroxidation. These reactions produce numerous species, some of which can be formed through more than one pathway. MS-based lipidomics offers the selectivity and sensitivity required for qualitative and quantitative analysis of multiple lipid species, in a variety of biological systems, and can facilitate the study of these mediators.

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Year:  2011        PMID： 21936796     DOI： 10.1042/BST0391240

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  32 in total

1.  Distribution of bioactive lipid mediators in human skin.

Authors:  Alexandra C Kendall; Suzanne M Pilkington; Karen A Massey; Gary Sassano; Lesley E Rhodes; Anna Nicolaou
Journal:  J Invest Dermatol       Date:  2015-02-10       Impact factor: 8.551

Review 2.  Oxidative lipidomics coming of age: advances in analysis of oxidized phospholipids in physiology and pathology.

Authors:  Corinne M Spickett; Andrew R Pitt
Journal:  Antioxid Redox Signal       Date:  2015-03-26       Impact factor: 8.401

Review 3.  New families of bioactive oxidized phospholipids generated by immune cells: identification and signaling actions.

Authors:  Valerie B O'Donnell; Robert C Murphy
Journal:  Blood       Date:  2012-07-16       Impact factor: 22.113

Review 4.  Dietary fat and heart failure: moving from lipotoxicity to lipoprotection.

Authors:  William C Stanley; Erinne R Dabkowski; Rogerio F Ribeiro; Kelly A O'Connell
Journal:  Circ Res       Date:  2012-03-02       Impact factor: 17.367

Review 5.  Activation of PPARδ: from computer modelling to biological effects.

Authors:  Shirin Kahremany; Ariela Livne; Arie Gruzman; Hanoch Senderowitz; Shlomo Sasson
Journal:  Br J Pharmacol       Date:  2014-12-15       Impact factor: 8.739

6.  Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.

Authors:  Valerian E Kagan; Gaowei Mao; Feng Qu; Jose Pedro Friedmann Angeli; Sebastian Doll; Claudette St Croix; Haider Hussain Dar; Bing Liu; Vladimir A Tyurin; Vladimir B Ritov; Alexandr A Kapralov; Andrew A Amoscato; Jianfei Jiang; Tamil Anthonymuthu; Dariush Mohammadyani; Qin Yang; Bettina Proneth; Judith Klein-Seetharaman; Simon Watkins; Ivet Bahar; Joel Greenberger; Rama K Mallampalli; Brent R Stockwell; Yulia Y Tyurina; Marcus Conrad; Hülya Bayır
Journal:  Nat Chem Biol       Date:  2016-11-14       Impact factor: 15.040

Review 7.  Paradigm shift - Metabolic transformation of docosahexaenoic and eicosapentaenoic acids to bioactives exemplify the promise of fatty acid drug discovery.

Authors:  Ganesh V Halade; Laurence M Black; Mahendra Kumar Verma
Journal:  Biotechnol Adv       Date:  2018-02-28       Impact factor: 14.227

Review 8.  The Nematode Caenorhabditis elegans as a Model Organism to Study Metabolic Effects of ω-3 Polyunsaturated Fatty Acids in Obesity.

Authors:  Amal Bouyanfif; Shasika Jayarathne; Iurii Koboziev; Naima Moustaid-Moussa
Journal:  Adv Nutr       Date:  2019-01-01       Impact factor: 8.701

9.  Bioactive lipid mediators in polycystic kidney disease.

Authors:  Jelena Klawitter; Jost Klawitter; Kim McFann; Alexander T Pennington; Kaleab Z Abebe; Godela Brosnahan; Melissa A Cadnapaphornchai; Michel Chonchol; Berenice Gitomer; Uwe Christians; Robert W Schrier
Journal:  J Lipid Res       Date:  2013-12-16       Impact factor: 5.922

10.  Metabolomic profiling of regulatory lipid mediators in sputum from adult cystic fibrosis patients.

Authors:  Jun Yang; Jason P Eiserich; Carroll E Cross; Brian M Morrissey; Bruce D Hammock
Journal:  Free Radic Biol Med       Date:  2012-05-08       Impact factor: 7.376
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