Literature DB >> 21936783

Cellular functions of class IX myosins in epithelia and immune cells.

Martin Bähler1, Kerstin Elfrink, Peter J Hanley, Sabine Thelen, Yan Xu.   

Abstract

Mammals contain two class IX myosins, Myo9a and Myo9b. They are actin-based motorized signalling molecules that negatively regulate RhoA signalling. Myo9a has been implicated in the regulation of epithelial cell morphology and differentiation, whereas Myo9b has been shown to play an important role in the regulation of macrophage shape and motility.

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Year:  2011        PMID： 21936783     DOI： 10.1042/BST0391166

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  7 in total

1.  Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism.

Authors:  Fengshuang Yi; Ruirui Kong; Jinqi Ren; Li Zhu; Jizhong Lou; Jane Y Wu; Wei Feng
Journal:  J Mol Biol       Date:  2016-06-27       Impact factor: 5.469

2.  Rho-GTPase Activating Protein myosin MYO9A identified as a novel candidate gene for monogenic focal segmental glomerulosclerosis.

Authors:  Qi Li; Ashima Gulati; Mathieu Lemaire; Timothy Nottoli; Allen Bale; Alda Tufro
Journal:  Kidney Int       Date:  2021-01-04       Impact factor: 10.612

3.  Regulation of collective cell migration by RhoGAP myosin IXA.

Authors:  Tatiana Omelchenko
Journal:  Small GTPases       Date:  2012-06-27

4.  Phenotypic analysis of Myo10 knockout (Myo10tm2/tm2) mice lacking full-length (motorized) but not brain-specific headless myosin X.

Authors:  Anne C Bachg; Markus Horsthemke; Boris V Skryabin; Tim Klasen; Nina Nagelmann; Cornelius Faber; Emma Woodham; Laura M Machesky; Sandra Bachg; Richard Stange; Hyun-Woo Jeong; Ralf H Adams; Martin Bähler; Peter J Hanley
Journal:  Sci Rep       Date:  2019-01-24       Impact factor: 4.379

Review 5.  Myosins in cell junctions.

Authors:  Katy C Liu; Richard E Cheney
Journal:  Bioarchitecture       Date:  2012-09-01

6.  The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity.

Authors:  Brooke K McMichael; Katharine F Scherer; Nicole C Franklin; Beth S Lee
Journal:  PLoS One       Date:  2014-01-23       Impact factor: 3.240

7.  Classification of clear cell renal cell carcinoma based on PKM alternative splicing.

Authors:  Xiangyu Li; Beste Turanli; Kajetan Juszczak; Woonghee Kim; Muhammad Arif; Yusuke Sato; Seishi Ogawa; Hasan Turkez; Jens Nielsen; Jan Boren; Mathias Uhlen; Cheng Zhang; Adil Mardinoglu
Journal:  Heliyon       Date:  2020-02-19
  7 in total

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