Literature DB >> 219354

Genesis of a virus-transforming gene.

J M Bishop, B Baker, D Fujita, P McCombe, D Sheiness, K Smith, D H Spector, D Stehelin, H E Varmus.   

Abstract

The gene src responsible for neoplastic transformation of fibroblasts by avian sarcoma viruses was apparently derived from highly conserved nucleotide sequences in the normal avian genome. The cellular homologue of src is unlinked to the genome of an endogenous virus in chicken cells and functions in an unknown manner during normal cell metabolism.

Entities:  

Mesh:

Year:  1978        PMID: 219354

Source DB:  PubMed          Journal:  Natl Cancer Inst Monogr        ISSN: 0083-1921


  6 in total

1.  A rat virus visits the clinic: translating basic discoveries into clinical medicine in the 21st century.

Authors:  C R Boland; A Goel
Journal:  Gut       Date:  2003-01       Impact factor: 23.059

2.  Src modulates contractile vascular smooth muscle function via regulation of focal adhesions.

Authors:  Jianghong Min; Maya Reznichenko; Ransom H Poythress; Cynthia M Gallant; Susanne Vetterkind; Yunping Li; Kathleen G Morgan
Journal:  J Cell Physiol       Date:  2012-11       Impact factor: 6.384

3.  Tumors induced in mice by direct inoculation of plasmid DNA expressing both activated H-ras and c-myc.

Authors:  Li Sheng-Fowler; Fang Cai; Haiqing Fu; Yong Zhu; Brian Orrison; Gideon Foseh; Don G Blair; Stephen H Hughes; John M Coffin; Andrew M Lewis; Keith Peden
Journal:  Int J Biol Sci       Date:  2010-03-29       Impact factor: 6.580

4.  Discovering tumor suppressor genes through genome-wide copy number analysis.

Authors:  S Michael Rothenberg; Jeff Settleman
Journal:  Curr Genomics       Date:  2010-08       Impact factor: 2.236

Review 5.  Adhesions Assemble!-Autoinhibition as a Major Regulatory Mechanism of Integrin-Mediated Adhesion.

Authors:  Rejina B Khan; Benjamin T Goult
Journal:  Front Mol Biosci       Date:  2019-12-17

Review 6.  Regulation of the SRC family kinases by Csk.

Authors:  Masato Okada
Journal:  Int J Biol Sci       Date:  2012-11-01       Impact factor: 6.580

  6 in total

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