| Literature DB >> 2193438 |
S Jentsch1, W Seufert, T Sommer, H A Reins.
Abstract
Covalent attachment of ubiquitin to cellular proteins is essential for cell viability and is catalysed by a set of distinct ubiquitin-conjugating enzymes. Individual members of this novel enzyme family mediate strikingly diverse functions, including DNA repair, cell cycle control, selective protein degradation and essential functions of the stress response.Mesh:
Substances:
Year: 1990 PMID: 2193438 DOI: 10.1016/0968-0004(90)90161-4
Source DB: PubMed Journal: Trends Biochem Sci ISSN: 0968-0004 Impact factor: 13.807