OBJECTIVE: To evaluate a group of spinocerebellar ataxia type 3 (SCA3) or Machado-Joseph disease (MJD) (SCA3/MJD) patients and assess whether there is an association between neuropathy and serum ferritin levels and restless legs syndrome (RLS). METHODS: Twenty-six SCA3/MJD patients underwent electromyography studies to check for neuropathy. Their serum ferritin levels were measured as well. These findings were evaluated based on the presence or not of RLS and its severity. RESULTS: The proportion of neuropathy in the RLS group was not significantly higher compared to the non-RLS group (23 vs. 15%, Fisher's exact test, p = 1.000). Furthermore, no association was found between RLS and ferritin levels. CONCLUSION: We found no correlation between neuropathy or ferritin levels and RLS in SCA3/MJD patients.
OBJECTIVE: To evaluate a group of spinocerebellar ataxia type 3 (SCA3) or Machado-Joseph disease (MJD) (SCA3/MJD) patients and assess whether there is an association between neuropathy and serum ferritin levels and restless legs syndrome (RLS). METHODS: Twenty-six SCA3/MJDpatients underwent electromyography studies to check for neuropathy. Their serum ferritin levels were measured as well. These findings were evaluated based on the presence or not of RLS and its severity. RESULTS: The proportion of neuropathy in the RLS group was not significantly higher compared to the non-RLS group (23 vs. 15%, Fisher's exact test, p = 1.000). Furthermore, no association was found between RLS and ferritin levels. CONCLUSION: We found no correlation between neuropathy or ferritin levels and RLS in SCA3/MJDpatients.
Authors: Marcio Luiz Escorcio Bezerra; José Luiz Pedroso; Pedro Braga-Neto; Agessandro Abrahao; Marcus Vinicius Cristino de Albuquerque; Franklin Roberto Pereira Borges; Maria Luiza Saraiva-Pereira; Laura Bannach Jardim; Nadia Iandoli de Oliveira Braga; Gilberto Mastrocola Manzano; Orlando G P Barsottini Journal: Cerebellum Date: 2016-12 Impact factor: 3.847
Authors: Maria-Efstratia Tsimpanouli; Anjesh Ghimire; Anna J Barget; Ridge Weston; Henry L Paulson; Maria do Carmo Costa; Brendon O Watson Journal: Cells Date: 2022-10-05 Impact factor: 7.666