Literature DB >> 21933001

Early resolution of type 2 diabetes seen after Roux-en-Y gastric bypass and vertical sleeve gastrectomy.

Brooke E Bayham1, Frank L Greenway, Drake E Bellanger, Carol E O'Neil.   

Abstract

BACKGROUND: Type 2 diabetes (T2D) accounts for the majority of diagnosed cases of diabetes in adults in the United States. Many of these individuals are also morbidly obese and choose to undergo bariatric surgery to lose weight and gain glycemic control. The Roux-en-Y gastric bypass (RYGB) has been shown to resolve diabetes before substantial weight loss occurs. Several studies suggest that the vertical sleeve gastrectomy (VSG), a newer bariatric operation, may result in comparable weight loss and rapid diabetes control.
METHODS: We conducted a retrospective chart review of 262 patients diagnosed with diabetes who underwent either the RYGB or the VSG between 2002 and 2010. Medication usage before and after surgery was recorded. Patients who discontinued all medications postoperatively were considered "resolved" of T2D, and those who reduced the number of medications were considered as "showing improvement" in their T2D. Peri- and postoperative complications were also recorded for each operation.
RESULTS: At 8 weeks postoperatively, follow-up data were available for 38 RYGB patients and 71 VSG patients. Approximately 79% of RYGB patients and 83% of VSG patients remained off their diabetes medication. VSG patients experienced a significantly lower incidence of major and minor complications both peri- and postoperatively compared with RYGB patients.
CONCLUSIONS: Both operations appear to equally resolve T2D in an obese, adult population; however, the incidence of both major and minor complications is much lower in the VSG patient group. Therefore, the VSG should also be considered as a treatment option for obese individuals with T2D.

Entities:  

Mesh:

Year:  2011        PMID: 21933001     DOI: 10.1089/dia.2011.0151

Source DB:  PubMed          Journal:  Diabetes Technol Ther        ISSN: 1520-9156            Impact factor:   6.118


  23 in total

1.  RYGB Is More Effective than VSG at Protecting Mice from Prolonged High-Fat Diet Exposure: An Occasion to Roll Up Our Sleeves?

Authors:  Matthew Stevenson; Ankita Srivastava; Jenny Lee; Christopher Hall; Thomas Palaia; Raymond Lau; Collin Brathwaite; Louis Ragolia
Journal:  Obes Surg       Date:  2021-04-15       Impact factor: 4.129

Review 2.  Ghrelin, the proglucagon-derived peptides and peptide YY in nutrient homeostasis.

Authors:  Charlotte X Dong; Patricia L Brubaker
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2012-10-02       Impact factor: 46.802

3.  Differential Acute Impacts of Sleeve Gastrectomy, Roux-en-Y Gastric Bypass Surgery and Matched Caloric Restriction Diet on Insulin Secretion, Insulin Effectiveness and Non-Esterified Fatty Acid Levels Among Patients with Type 2 Diabetes.

Authors:  Felicity Thomas; Greg C Smith; Jun Lu; Richard Babor; Michael Booth; Grant Beban; J Geoffrey Chase; Rinki Murphy
Journal:  Obes Surg       Date:  2016-08       Impact factor: 4.129

4.  Metabolic effects of Roux-en-Y gastric bypass in obese adolescents and young adults.

Authors:  Manasi Sinha; Takara L Stanley; Jessica Webb; Christina Scirica; Kathleen Corey; Janey Pratt; Paul A Boepple; Alison Hoppin; Madhusmita Misra
Journal:  J Pediatr Gastroenterol Nutr       Date:  2013-05       Impact factor: 2.839

Review 5.  Gastric bypass and sleeve gastrectomy for type 2 diabetes: a systematic review and meta-analysis of outcomes.

Authors:  Shelley Yip; Lindsay D Plank; Rinki Murphy
Journal:  Obes Surg       Date:  2013-12       Impact factor: 4.129

6.  Medication Use Among Patients Prior to Bariatric Surgery.

Authors:  Jennifer Padden Elliott; Erica L Gray; Jessie Yu; Melissa A Kalarchian
Journal:  Bariatr Surg Pract Patient Care       Date:  2015-09-01       Impact factor: 0.607

Review 7.  Effects of bariatric surgery on glucose homeostasis and type 2 diabetes.

Authors:  David Bradley; Faidon Magkos; Samuel Klein
Journal:  Gastroenterology       Date:  2012-08-08       Impact factor: 22.682

8.  Bariatric surgery as a treatment option in patients with type 2 diabetes mellitus.

Authors:  Marianna Spanou; Konstantinos Tziomalos
Journal:  World J Diabetes       Date:  2013-04-15

9.  Improved rodent maternal metabolism but reduced intrauterine growth after vertical sleeve gastrectomy.

Authors:  Bernadette E Grayson; Katarina M Schneider; Stephen C Woods; Randy J Seeley
Journal:  Sci Transl Med       Date:  2013-08-21       Impact factor: 17.956

10.  Improvements in hippocampal-dependent memory and microglial infiltration with calorie restriction and gastric bypass surgery, but not with vertical sleeve gastrectomy.

Authors:  B E Grayson; M F Fitzgerald; A P Hakala-Finch; V M Ferris; D P Begg; J Tong; S C Woods; R J Seeley; T L Davidson; S C Benoit
Journal:  Int J Obes (Lond)       Date:  2013-05-27       Impact factor: 5.095

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.