Literature DB >> 21931323

Heterogeneity in simvastatin-induced cytotoxicity in AML is caused by differences in Ras-isoprenylation.

K van der Weide, P M Korthuis, F Kuipers, E G E de Vries, E Vellenga.   

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Year:  2011        PMID： 21931323     DOI： 10.1038/leu.2011.259

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  4 in total

1.  Simvastatin interacts synergistically with tipifarnib to induce apoptosis in leukemia cells through the disruption of RAS membrane localization and ERK pathway inhibition.

Authors:  Tamer A Ahmed; John Hayslip; Markos Leggas
Journal:  Leuk Res       Date:  2014-09-16       Impact factor: 3.156

2.  Anti-leukemic effects of simvastatin on NRASG12D mutant acute myeloid leukemia cells.

Authors:  Jiryeon Jang; Jeeyun Lee; Jun Ho Jang; Chul Won Jung; Silvia Park
Journal:  Mol Biol Rep       Date:  2019-08-26       Impact factor: 2.316

Review 3.  The role of cholesterol metabolism in leukemia.

Authors:  Liang Zhao; Huien Zhan; Xinya Jiang; Yangqiu Li; Hui Zeng
Journal:  Blood Sci       Date:  2019-09-17

4.  Simvastatin regulates the proliferation, apoptosis, migration and invasion of human acute myeloid leukemia cells via miR-19a-3p/HIF-1α axis.

Authors:  Hua Tian; Tiao Qiang; Jinbo Wang; Li Ji; Bo Li
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269
  4 in total

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