| Literature DB >> 21928782 |
Jing Xu1, Yuanqiang Guo, Chunfeng Xie, Yushan Li, Jie Gao, Tiejun Zhang, Wenbin Hou, Lingzhi Fang, Liping Gui.
Abstract
Ten myrsinol diterpenes, euphorbiaproliferins A-J (1-10), along with nine known analogues (11-19) were isolated from the roots of Euphorbia prolifera. Their structures were elucidated by spectroscopic data analysis (IR, ESIMS, HRESIMS, 1D and 2D NMR), and the structure of 1 was confirmed by X-ray crystallography. The diterpenes showed neuroprotective effects against MPP+-induced neuronal cell death in SH-SY5Y cells.Entities:
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Year: 2011 PMID： 21928782 DOI： 10.1021/np200591h
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050