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Literature DB >> 21928452

Identification of α2 macroglobulin as a major serum ghrelin esterase.

Lisa M Eubanks¹, G Neil Stowe, Sandra De Lamo Marin, Alexander V Mayorov, Mark S Hixon, Kim D Janda.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2011 PMID： 21928452 PMCID： PMC3515674 DOI： 10.1002/anie.201104512

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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19 in total

1. Profiling enzyme activities in vivo using click chemistry methods.

Authors: Anna E Speers; Benjamin F Cravatt
Journal: Chem Biol Date: 2004-04

2. Epidemiologic and economic consequences of the global epidemics of obesity and diabetes.

Authors: Derek Yach; David Stuckler; Kelly D Brownell
Journal: Nat Med Date: 2006-01 Impact factor: 53.440

3. Construction of human ghrelin receptor (hGHS-R1a) model using a fragmental prediction approach and validation through docking analysis.

Authors: Alessandro Pedretti; Marco Villa; Marco Pallavicini; Ermanno Valoti; Giulio Vistoli
Journal: J Med Chem Date: 2006-06-01 Impact factor: 7.446

Review 4. The ghrelin O-acyltransferase-ghrelin system: a novel regulator of glucose metabolism.

Authors: Kristy M Heppner; Jenny Tong; Henriette Kirchner; Ralf Nass; Matthias H Tschöp
Journal: Curr Opin Endocrinol Diabetes Obes Date: 2011-02 Impact factor: 3.243

5. Ghrelin is a growth-hormone-releasing acylated peptide from stomach.

Authors: M Kojima; H Hosoda; Y Date; M Nakazato; H Matsuo; K Kangawa
Journal: Nature Date: 1999-12-09 Impact factor: 49.962

6. Lysophospholipase I identified as a ghrelin deacylation enzyme in rat stomach.

Authors: Yuka Shanado; Motohiko Kometani; Hidefumi Uchiyama; Shinichi Koizumi; Naoki Teno
Journal: Biochem Biophys Res Commun Date: 2004-12-24 Impact factor: 3.575

7. Ghrelin degradation by serum and tissue homogenates: identification of the cleavage sites.

Authors: Carine De Vriese; Francoise Gregoire; Roger Lema-Kisoka; Magali Waelbroeck; Patrick Robberecht; Christine Delporte
Journal: Endocrinology Date: 2004-07-15 Impact factor: 4.736

8. Effect of tellurium position on the myocardial uptake of radioiodinated 18-iodotellura-17-octadecenoic acid analogues.

Authors: F F Knapp; P C Srivastava; A P Callahan; E B Cunningham; G W Kabalka; K A Sastry
Journal: J Med Chem Date: 1984-01 Impact factor: 7.446

Review 6. Ghrelin octanoylation by ghrelin O-acyltransferase: protein acylation impacting metabolic and neuroendocrine signalling.

Authors: Tasha R Davis; Mariah R Pierce; Sadie X Novak; James L Hougland
Journal: Open Biol Date: 2021-07-28 Impact factor: 6.411

6 in total

Identification of α2 macroglobulin as a major serum ghrelin esterase.

1. Profiling enzyme activities in vivo using click chemistry methods.

2. Epidemiologic and economic consequences of the global epidemics of obesity and diabetes.

3. Construction of human ghrelin receptor (hGHS-R1a) model using a fragmental prediction approach and validation through docking analysis.

Review 4. The ghrelin O-acyltransferase-ghrelin system: a novel regulator of glucose metabolism.

5. Ghrelin is a growth-hormone-releasing acylated peptide from stomach.

6. Lysophospholipase I identified as a ghrelin deacylation enzyme in rat stomach.

7. Ghrelin degradation by serum and tissue homogenates: identification of the cleavage sites.

8. Effect of tellurium position on the myocardial uptake of radioiodinated 18-iodotellura-17-octadecenoic acid analogues.

Review 9. Alpha 2-macroglobulin, a multifunctional binding protein with targeting characteristics.

10. Primary structure of human alpha 2-macroglobulin. V. The complete structure.

Review 1. Ghrelin Signaling: GOAT and GHS-R1a Take a LEAP in Complexity.

2. Late-Stage Conversion of Diphenylphosphonate to Fluorophosphonate Probes for the Investigation of Serine Hydrolases.

3. Development of Esterase-Resistant and Highly Active Ghrelin Analogs via Thiol-Ene Click Chemistry.

Review 4. A Not-So-Ancient Grease History: Click Chemistry and Protein Lipid Modifications.

Review 5. Ghrelin Acylation-A Post-Translational Tuning Mechanism Regulating Adult Hippocampal Neurogenesis.

Review 6. Ghrelin octanoylation by ghrelin O-acyltransferase: protein acylation impacting metabolic and neuroendocrine signalling.