BACKGROUND: This study was performed to define prognostic factors and management of minor salivary gland carcinoma of the oral cavity and oropharynx . METHODS: Retrospective analyses of patients with salivary gland carcinoma of the oral cavity or oropharynx, treated in 1989 to 2006. Statistics included univariate analyses to identify prognostic factors associated with disease-free survival (DFS) and disease-specific survival. A multivariate analysis model was constructed by the Cox method. RESULTS: Seventy-seven patients constituted our cohort. Significant prognostic factors regarding DFS and disease-specific survival in univariate analyses comprised tumor size, surgical margins, grade, lymph node status, and Karnofsky status and T classification. A multivariate model identified tumor size, grade, surgical margins, and lymph node status significant regarding DFS. CONCLUSIONS: Tumor size, grade, surgical margins, and lymph node status could be used for a rational design of treatment strategies in these rare tumors.
BACKGROUND: This study was performed to define prognostic factors and management of minor salivary gland carcinoma of the oral cavity and oropharynx . METHODS: Retrospective analyses of patients with salivary gland carcinoma of the oral cavity or oropharynx, treated in 1989 to 2006. Statistics included univariate analyses to identify prognostic factors associated with disease-free survival (DFS) and disease-specific survival. A multivariate analysis model was constructed by the Cox method. RESULTS: Seventy-seven patients constituted our cohort. Significant prognostic factors regarding DFS and disease-specific survival in univariate analyses comprised tumor size, surgical margins, grade, lymph node status, and Karnofsky status and T classification. A multivariate model identified tumor size, grade, surgical margins, and lymph node status significant regarding DFS. CONCLUSIONS:Tumor size, grade, surgical margins, and lymph node status could be used for a rational design of treatment strategies in these rare tumors.
Authors: Georg Haymerle; Sven Schneider; Luke Harris; Theresia Häupl; Christian Schopper; Johannes Pammer; Matthaeus Ch Grasl; Boban M Erovic Journal: Eur Arch Otorhinolaryngol Date: 2015-10-23 Impact factor: 2.503
Authors: David W Schoppy; Michael E Kupferman; Amy C Hessel; Diana M Bell; Elizabeth M Garland; Edward J Damrose; F Christopher Holsinger Journal: Cancers Head Neck Date: 2017-05-31