Potentiation of lithium with carbamazepine in acute mania.

In a 6 month prospective randomized open trial addition of 400 mgs. of carbamazepine per day to lithium carbonate was assessed. Although statistically non-significant, the trends suggest that use of carbamazepine hastens recovery and leads to less frequent use of emergency sedation without any increase in side effects.

RCT Entities:   Population Interventions Outcomes