Literature DB >> 21926199

Rapid screening method for compounds that affect the growth and germination of Candida albicans, using a real-time PCR thermocycler.

Lucja M Jarosz1, Bastiaan P Krom.   

Abstract

We propose a screening method for compounds affecting growth and germination in Candida albicans using a real-time PCR thermocycler to quantify green fluorescent protein (GFP) fluorescence. Using P(ACT1)-GFP and P(HWP1)-GFP reporter strains, the effects of a wide range of compounds on growth and hyphal formation were quantitatively assessed within 3 h after inoculation.

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Year:  2011        PMID： 21926199      PMCID： PMC3208978          DOI： 10.1128/AEM.06227-11

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  22 in total

1.  Yeast-enhanced green fluorescent protein (yEGFP): a reporter of gene expression in Candida albicans.

Authors:  Brendan P Cormack; Gwyneth Bertram; Mark Egerton; Neil A R Gow; Stanley Falkow; Alistair J P Brown
Journal:  Microbiology (Reading)       Date:  1997-02       Impact factor: 2.777

2.  Isogenic strain construction and gene mapping in Candida albicans.

Authors:  W A Fonzi; M Y Irwin
Journal:  Genetics       Date:  1993-07       Impact factor: 4.562

3.  Developmental expression of a tandemly repeated, proline-and glutamine-rich amino acid motif on hyphal surfaces on Candida albicans.

Authors:  J F Staab; C A Ferrer; P Sundstrom
Journal:  J Biol Chem       Date:  1996-03-15       Impact factor: 5.157

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Authors:  F C Odds; C A Hall; A B Abbott
Journal:  Sabouraudia       Date:  1978-12

5.  Effect of amphotericin B, fluconazole and itraconazole on intracellular Candida albicans and germ tube development in macrophages.

Authors:  J W Van 't Wout; I Meynaar; I Linde; R Poell; H Mattie; R Van Furth
Journal:  J Antimicrob Chemother       Date:  1990-05       Impact factor: 5.790

6.  Denture stomatitis: a role for Candida biofilms.

Authors:  Gordon Ramage; Kelley Tomsett; Brian L Wickes; José L López-Ribot; Spencer W Redding
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2004-07

7.  Inoculum size effect in dimorphic fungi: extracellular control of yeast-mycelium dimorphism in Ceratocystis ulmi.

Authors:  Jacob M Hornby; Sarah M Jacobitz-Kizzier; Donna J McNeel; Ellen C Jensen; David S Treves; Kenneth W Nickerson
Journal:  Appl Environ Microbiol       Date:  2004-03       Impact factor: 4.792

8.  Tyrosol is a quorum-sensing molecule in Candida albicans.

Authors:  Hao Chen; Masaki Fujita; Qinghua Feng; Jon Clardy; Gerald R Fink
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-29       Impact factor: 11.205

9.  Integrative, multifunctional plasmids for hypha-specific or constitutive expression of green fluorescent protein in Candida albicans.

Authors:  Janet F Staab; Yong-Sun Bahn; Paula Sundstrom
Journal:  Microbiology       Date:  2003-10       Impact factor: 2.777

10.  GFP as a quantitative reporter of gene regulation in Candida albicans.

Authors:  Caroline J Barelle; Claire L Manson; Donna M MacCallum; Frank C Odds; Neil A R Gow; Alistair J P Brown
Journal:  Yeast       Date:  2004-03       Impact factor: 3.239
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  2 in total

1.  In vitro and in vivo activity of a novel antifungal small molecule against Candida infections.

Authors:  Sarah Sze Wah Wong; Richard Yi Tsun Kao; Kwok Yong Yuen; Yu Wang; Dan Yang; Lakshman Perera Samaranayake; Chaminda Jayampath Seneviratne
Journal:  PLoS One       Date:  2014-01-22       Impact factor: 3.240

2.  AI-2 of Aggregatibacter actinomycetemcomitans inhibits Candida albicans biofilm formation.

Authors:  Endang W Bachtiar; Boy M Bachtiar; Lucja M Jarosz; Lisa R Amir; Hari Sunarto; Hadas Ganin; Michael M Meijler; Bastiaan P Krom
Journal:  Front Cell Infect Microbiol       Date:  2014-07-21       Impact factor: 5.293
  2 in total

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