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Literature DB >> 2192552

Safety and efficacy of loperamide.

Abstract

Loperamide is a safe and effective antidiarrheal for the treatment of acute diarrhea. Efficacy data suggest that loperamide is more effective than the prescription drug diphenoxylate and an over-the-counter bismuth subsalicylate preparation. Loperamide is a safe drug, with few adverse reactions reported worldwide. It also lacks significant abuse potential. Loperamide may prove to be the antidiarrheal agent of choice when compared with currently available nonprescription treatments for acute diarrhea.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1990 PMID： 2192552 DOI： 10.1016/0002-9343(90)90269-j

Source DB: PubMed Journal: Am J Med ISSN： 0002-9343 Impact factor: 4.965

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Cited

11 in total

Review 1. [Treating travelers' diarrhea. When should medication be given?].

Authors: G Birkenfeld
Journal: Internist (Berl) Date: 2007-12 Impact factor: 0.743

2. PREDOSE: a semantic web platform for drug abuse epidemiology using social media.

Authors: Delroy Cameron; Gary A Smith; Raminta Daniulaityte; Amit P Sheth; Drashti Dave; Lu Chen; Gaurish Anand; Robert Carlson; Kera Z Watkins; Russel Falck
Journal: J Biomed Inform Date: 2013-07-25 Impact factor: 6.317

Review 3. Opioid analgesics and P-glycoprotein efflux transporters: a potential systems-level contribution to analgesic tolerance.

Authors: Susan L Mercer; Andrew Coop
Journal: Curr Top Med Chem Date: 2011 Impact factor: 3.295

Safety and efficacy of loperamide.

Review 1. [Treating travelers' diarrhea. When should medication be given?].

2. PREDOSE: a semantic web platform for drug abuse epidemiology using social media.

Review 3. Opioid analgesics and P-glycoprotein efflux transporters: a potential systems-level contribution to analgesic tolerance.

Review 4. Secretory diarrhoea: mechanisms and emerging therapies.

5. "I just wanted to tell you that loperamide WILL WORK": a web-based study of extra-medical use of loperamide.

6. Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis.

7. Ventricular fibrillation due to overdose of loperamide, the "poor man's methadone".

8. Fluoroscopic Characterization of Colonic Dysmotility Associated to Opioid and Cannabinoid Agonists in Conscious Rats.

9. Secondary prophylaxis of docetaxel induced diarrhea with loperamide: case report.

10. Bradycardia and Syncope in a Patient Presenting With Loperamide Abuse.