Literature DB >> 21924166

Single nucleotide polymorphism (SNP) panels for rapid positional cloning in zebrafish.

Matthew D Clark1, Victor Guryev, Ewart de Bruijn, Isaac J Nijman, Masazumi Tada, Catherine Wilson, Panos Deloukas, John H Postlethwait, Edwin Cuppen, Derek L Stemple.   

Abstract

Despite considerable genetic and genomic resources the positional cloning of forward mutations remains a slow and manually intensive task, typically using gel based genotyping and sequential rounds of mapping. We have used the latest genetic resources and genotyping technologies to develop two commercially available SNP panels of thousands of markers that can be used to speed up positional cloning.
Copyright © 2011 Elsevier Inc. All rights reserved.

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Year:  2011        PMID: 21924166     DOI: 10.1016/B978-0-12-374814-0.00013-6

Source DB:  PubMed          Journal:  Methods Cell Biol        ISSN: 0091-679X            Impact factor:   1.441


  3 in total

1.  Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing.

Authors:  Nikolaus Obholzer; Ian A Swinburne; Evan Schwab; Alex V Nechiporuk; Teresa Nicolson; Sean G Megason
Journal:  Development       Date:  2012-10-10       Impact factor: 6.868

2.  An ENU mutagenesis screen in zebrafish for visual system mutants identifies a novel splice-acceptor site mutation in patched2 that results in Colobomas.

Authors:  Jiwoon Lee; Ben D Cox; Christina M S Daly; Chanjae Lee; Richard J Nuckels; Rachel K Tittle; Rosa A Uribe; Jeffrey M Gross
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-12-13       Impact factor: 4.799

3.  Localization of causal locus in the genome of the brown macroalga Ectocarpus: NGS-based mapping and positional cloning approaches.

Authors:  Bernard Billoud; Émilie Jouanno; Zofia Nehr; Baptiste Carton; Élodie Rolland; Sabine Chenivesse; Bénédicte Charrier
Journal:  Front Plant Sci       Date:  2015-02-19       Impact factor: 5.753

  3 in total

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