Literature DB >> 2192267

Transfected human beta-polymerase promoter contains a ras-responsive element.

P S Kedar1, D R Lowy, S G Widen, S H Wilson.   

Abstract

beta-Polymerase is a vertebrate cellular DNA polymerase involved in gap-filling synthesis during some types of genomic DNA repair. We report that a cloned human beta-polymerase promoter in a transient expression assay is activated by p21v-rasH expression in NIH 3T3 cells. A decanucleotide palindromic element, GTGACGTCAC, at positions -49 to -40 in the promoter is required for this ras-mediated stimulation.

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Year:  1990        PMID： 2192267      PMCID： PMC360856          DOI： 10.1128/mcb.10.7.3852-3856.1990

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  36 in total

1.  Protein binding elements in the human beta-polymerase promoter.

Authors:  E W Englander; S H Wilson
Journal:  Nucleic Acids Res       Date:  1990-02-25       Impact factor: 16.971

2.  A new technique for the assay of infectivity of human adenovirus 5 DNA.

Authors:  F L Graham; A J van der Eb
Journal:  Virology       Date:  1973-04       Impact factor: 3.616

3.  Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses.

Authors:  C J Der; T G Krontiris; G M Cooper
Journal:  Proc Natl Acad Sci U S A       Date:  1982-06       Impact factor: 11.205

4.  Oncogene-induced transformation of C3H 10T1/2 cells is enhanced by tumor promoters.

Authors:  W L Hsiao; S Gattoni-Celli; I B Weinstein
Journal:  Science       Date:  1984-11-02       Impact factor: 47.728

5.  Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.

Authors:  J Preiss; C R Loomis; W R Bishop; R Stein; J E Niedel; R M Bell
Journal:  J Biol Chem       Date:  1986-07-05       Impact factor: 5.157

6.  The p21 ras C-terminus is required for transformation and membrane association.

Authors:  B M Willumsen; A Christensen; N L Hubbert; A G Papageorge; D R Lowy
Journal:  Nature       Date:  1984 Aug 16-22       Impact factor: 49.962

7.  Functional organization of the Harvey murine sarcoma virus genome.

Authors:  E H Chang; J M Maryak; C M Wei; T Y Shih; R Shober; H L Cheung; R W Ellis; G L Hager; E M Scolnick; D R Lowy
Journal:  J Virol       Date:  1980-07       Impact factor: 5.103

8.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

Authors:  C M Gorman; L F Moffat; B H Howard
Journal:  Mol Cell Biol       Date:  1982-09       Impact factor: 4.272

9.  Transforming p21 ras protein: flexibility in the major variable region linking the catalytic and membrane-anchoring domains.

Authors:  B M Willumsen; A G Papageorge; N Hubbert; E Bekesi; H F Kung; D R Lowy
Journal:  EMBO J       Date:  1985-11       Impact factor: 11.598

10.  Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.

Authors:  B M Willumsen; K Norris; A G Papageorge; N L Hubbert; D R Lowy
Journal:  EMBO J       Date:  1984-11       Impact factor: 11.598
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  7 in total

1.  Activation of the mouse DNA polymerase beta gene promoter by adenovirus type 12 E1A proteins.

Authors:  M Yamaguchi; Y Hayashi; F Hirose; K Shiroki; A Matsukage
Journal:  Nucleic Acids Res       Date:  1992-05-11       Impact factor: 16.971

2.  Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionein.

Authors:  K J Scanlon; L Jiao; T Funato; W Wang; T Tone; J J Rossi; M Kashani-Sabet
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-01       Impact factor: 11.205

3.  Upstream CREs participate in the basal activity of minute virus of mice promoter P4 and in its stimulation in ras-transformed cells.

Authors:  M Perros; L Deleu; J M Vanacker; Z Kherrouche; N Spruyt; S Faisst; J Rommelaere
Journal:  J Virol       Date:  1995-09       Impact factor: 5.103

4.  Attenuation of glucocorticoid receptor levels by the H-ras oncogene.

Authors:  V R Martins; M M Brentani; P R Housley
Journal:  Endocrine       Date:  1995-04       Impact factor: 3.633

5.  A novel mechanism of Ha-ras oncogene action: regulation of fibronectin mRNA levels by a nuclear posttranscriptional event.

Authors:  L A Chandler; C P Ehretsmann; S Bourgeois
Journal:  Mol Cell Biol       Date:  1994-05       Impact factor: 4.272

6.  Mammalian beta-polymerase promoter: phosphorylation of ATF/CRE-binding protein and regulation of DNA binding.

Authors:  E W Englander; S G Widen; S H Wilson
Journal:  Nucleic Acids Res       Date:  1991-06-25       Impact factor: 16.971

7.  Identification of a ras-activated enhancer in the mouse osteopontin promoter and its interaction with a putative ETS-related transcription factor whose activity correlates with the metastatic potential of the cell.

Authors:  X Guo; Y P Zhang; D A Mitchell; D T Denhardt; A F Chambers
Journal:  Mol Cell Biol       Date:  1995-01       Impact factor: 4.272
  7 in total

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