Literature DB >> 21922059

Modeling of chromosomal epigenetic silencing processes.

Attila Becskei1, Simone Scherrer, Janos Z Kelemen, Ann Ehrenhofer Murray.   

Abstract

Silenced genes in eukaryotes are packaged into heterochromatin. In addition to establishing a passive storage site for inactive genes in differentiated cells, silencing can play an active role in promoting cellular differentiation. Here, we describe quantitative modeling of silencing processes.

Year:  2011        PMID： 21922059      PMCID： PMC3173684          DOI： 10.4161/trns.2.4.16344

Source DB:  PubMed          Journal:  Transcription        ISSN： 2154-1272


  30 in total

1.  Conversion of graded to binary response in an activator-repressor system.

Authors:  Rajesh Karmakar
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2010-02-03

Review 2.  Polycomb silencing mechanisms and the management of genomic programmes.

Authors:  Yuri B Schwartz; Vincenzo Pirrotta
Journal:  Nat Rev Genet       Date:  2007-01       Impact factor: 53.242

3.  Synergy of repression and silencing gradients along the chromosome.

Authors:  Prasuna Ratna; Simone Scherrer; Christoph Fleischli; Attila Becskei
Journal:  J Mol Biol       Date:  2009-02-20       Impact factor: 5.469

4.  Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae.

Authors:  J Xie; M Pierce; V Gailus-Durner; M Wagner; E Winter; A K Vershon
Journal:  EMBO J       Date:  1999-11-15       Impact factor: 11.598

5.  PCNA connects DNA replication to epigenetic inheritance in yeast.

Authors:  Z Zhang; K Shibahara; B Stillman
Journal:  Nature       Date:  2000-11-09       Impact factor: 49.962

6.  Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase.

Authors:  S Imai; C M Armstrong; M Kaeberlein; L Guarente
Journal:  Nature       Date:  2000-02-17       Impact factor: 49.962

7.  Identification of sites required for repression of a silent mating type locus in yeast.

Authors:  J B Feldman; J B Hicks; J R Broach
Journal:  J Mol Biol       Date:  1984-10-05       Impact factor: 5.469

8.  Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast.

Authors:  A Hecht; T Laroche; S Strahl-Bolsinger; S M Gasser; M Grunstein
Journal:  Cell       Date:  1995-02-24       Impact factor: 41.582

9.  The Sir2-Sum1 complex represses transcription using both promoter-specific and long-range mechanisms to regulate cell identity and sexual cycle in the yeast Kluyveromyces lactis.

Authors:  Meleah A Hickman; Laura N Rusche
Journal:  PLoS Genet       Date:  2009-11-06       Impact factor: 5.917

10.  Computational modeling of the hematopoietic erythroid-myeloid switch reveals insights into cooperativity, priming, and irreversibility.

Authors:  Vijay Chickarmane; Tariq Enver; Carsten Peterson
Journal:  PLoS Comput Biol       Date:  2009-01-23       Impact factor: 4.475
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  1 in total

Review 1.  Epigenetic memories: structural marks or active circuits?

Authors:  Floriane Nicol-Benoît; Pascale Le-Goff; Yves Le-Dréan; Florence Demay; Farzad Pakdel; Gilles Flouriot; Denis Michel
Journal:  Cell Mol Life Sci       Date:  2012-02-14       Impact factor: 9.261
  1 in total

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