Literature DB >> 21921935

A genetic in vivo system to detect asymmetrically distributed RNA.

N JayaNandanan1, Elizabeth R Gavis, Veit Riechmann, Maria Leptin.   

Abstract

Many RNAs show polarized or otherwise non-random subcellular distributions. To create a method for genome-wide genetic screens for RNAs with asymmetric subcellular distributions, we have combined methods for gene tagging and live imaging of messenger RNA (mRNA). A pilot screen in a highly polarized, differentiated cell in the Drosophila larva, the branched terminal cell of the tracheal system, demonstrates the feasibility of the method for identifying new asymmetrically localized mRNAs in vivo.

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Year:  2011        PMID： 21921935      PMCID： PMC3207103          DOI： 10.1038/embor.2011.178

Source DB:  PubMed          Journal:  EMBO Rep        ISSN： 1469-221X            Impact factor:   8.807


  30 in total

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Authors:  P Rørth
Journal:  Mech Dev       Date:  1998-11       Impact factor: 1.882

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Authors:  Eric Lécuyer; Aleksandar S Necakov; Lucía Cáceres; Henry M Krause
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3.  Tribbles coordinates mitosis and morphogenesis in Drosophila by regulating string/CDC25 proteolysis.

Authors:  J Mata; S Curado; A Ephrussi; P Rørth
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4.  A pump-independent function of the Na,K-ATPase is required for epithelial junction function and tracheal tube-size control.

Authors:  Sarah M Paul; Michael J Palladino; Greg J Beitel
Journal:  Development       Date:  2007-01       Impact factor: 6.868

5.  Different levels of the homeodomain protein cut regulate distinct dendrite branching patterns of Drosophila multidendritic neurons.

Authors:  Wesley B Grueber; Lily Y Jan; Yuh Nung Jan
Journal:  Cell       Date:  2003-03-21       Impact factor: 41.582

6.  The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes.

Authors:  Hugo J Bellen; Robert W Levis; Guochun Liao; Yuchun He; Joseph W Carlson; Garson Tsang; Martha Evans-Holm; P Robin Hiesinger; Karen L Schulze; Gerald M Rubin; Roger A Hoskins; Allan C Spradling
Journal:  Genetics       Date:  2004-06       Impact factor: 4.562

7.  A Dynein-dependent shortcut rapidly delivers axis determination transcripts into the Drosophila oocyte.

Authors:  Alejandra Clark; Carine Meignin; Ilan Davis
Journal:  Development       Date:  2007-04-18       Impact factor: 6.868

8.  Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.

Authors:  A H Brand; N Perrimon
Journal:  Development       Date:  1993-06       Impact factor: 6.868

9.  The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic region required for tracheal development.

Authors:  M Affolter; J Montagne; U Walldorf; J Groppe; U Kloter; M LaRosa; W J Gehring
Journal:  Development       Date:  1994-04       Impact factor: 6.868

10.  The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system.

Authors:  K Guillemin; J Groppe; K Ducker; R Treisman; E Hafen; M Affolter; M A Krasnow
Journal:  Development       Date:  1996-05       Impact factor: 6.868
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  5 in total

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Review 3.  New methods to image transcription in living fly embryos: the insights so far, and the prospects.

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4.  Maintenance of Miranda Localization in Drosophila Neuroblasts Involves Interaction with the Cognate mRNA.

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Journal:  Curr Biol       Date:  2017-07-06       Impact factor: 10.834

5.  A Genome-Wide Screen for Dendritically Localized RNAs Identifies Genes Required for Dendrite Morphogenesis.

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  5 in total

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