Literature DB >> 21921924

Signatures for drug repositioning.

Charlotte Harrison.   

Abstract

Year:  2011        PMID： 21921924     DOI： 10.1038/nrg3076

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN： 1471-0056            Impact factor:   53.242


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  2 in total

1.  Discovery and preclinical validation of drug indications using compendia of public gene expression data.

Authors:  Marina Sirota; Joel T Dudley; Jeewon Kim; Annie P Chiang; Alex A Morgan; Alejandro Sweet-Cordero; Julien Sage; Atul J Butte
Journal:  Sci Transl Med       Date:  2011-08-17       Impact factor: 17.956

2.  Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease.

Authors:  Joel T Dudley; Marina Sirota; Mohan Shenoy; Reetesh K Pai; Silke Roedder; Annie P Chiang; Alex A Morgan; Minnie M Sarwal; Pankaj Jay Pasricha; Atul J Butte
Journal:  Sci Transl Med       Date:  2011-08-17       Impact factor: 17.956
  2 in total
  7 in total

1.  A c-Myc activation sensor-based high-throughput drug screening identifies an antineoplastic effect of nitazoxanide.

Authors:  Hua Fan-Minogue; Sandhya Bodapati; David Solow-Cordero; Alice Fan; Ramasamy Paulmurugan; Tarik F Massoud; Dean W Felsher; Sanjiv S Gambhir
Journal:  Mol Cancer Ther       Date:  2013-07-03       Impact factor: 6.261

2.  Using VisANT to Analyze Networks.

Authors:  Zhenjun Hu
Journal:  Curr Protoc Bioinformatics       Date:  2014

3.  Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain.

Authors:  Xiaohui Wang; Peter M Grace; Michael N Pham; Kui Cheng; Keith A Strand; Christina Smith; Jing Li; Linda R Watkins; Hang Yin
Journal:  FASEB J       Date:  2013-04-08       Impact factor: 5.191

4.  DrugSig: A resource for computational drug repositioning utilizing gene expression signatures.

Authors:  Hongyu Wu; Jinjiang Huang; Yang Zhong; Qingshan Huang
Journal:  PLoS One       Date:  2017-05-31       Impact factor: 3.240

5.  Transcriptional data: a new gateway to drug repositioning?

Authors:  Francesco Iorio; Timothy Rittman; Hong Ge; Michael Menden; Julio Saez-Rodriguez
Journal:  Drug Discov Today       Date:  2012-08-07       Impact factor: 7.851

6.  VisANT 4.0: Integrative network platform to connect genes, drugs, diseases and therapies.

Authors:  Zhenjun Hu; Yi-Chien Chang; Yan Wang; Chia-Ling Huang; Yang Liu; Feng Tian; Brian Granger; Charles Delisi
Journal:  Nucleic Acids Res       Date:  2013-05-28       Impact factor: 16.971

7.  Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality.

Authors:  Hua Xu; Melinda C Aldrich; Qingxia Chen; Hongfang Liu; Neeraja B Peterson; Qi Dai; Mia Levy; Anushi Shah; Xue Han; Xiaoyang Ruan; Min Jiang; Ying Li; Jamii St Julien; Jeremy Warner; Carol Friedman; Dan M Roden; Joshua C Denny
Journal:  J Am Med Inform Assoc       Date:  2014-07-22       Impact factor: 4.497
  7 in total

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