Literature DB >> 21920671

Premature ejaculation and other sexual dysfunctions in opiate dependent men receiving methadone substitution treatment.

Venkat Chekuri1, David Gerber, Adam Brodie, Rajeev Krishnadas.   

Abstract

BACKGROUND: A significant number of men with opiate misuse have sexual problems. Premature ejaculation (PE) occurs predominantly on discontinuation of the opiate but seems to persist in some cases. The aims of this study were to determine the rates of PE and other sexual dysfunctions in patients maintained on methadone; to determine the time of onset of PE in relation to onset of opiate misuse; and to look at the patients' perception of the effect of heroin and methadone on PE.
METHODS: Sixty five men attending a tertiary referral clinic for methadone maintenance treatment were assessed cross-sectionally using a semi-structured questionnaire, clinical interview, review of clinical records and the International Index of Erectile Function (IIEF).
RESULTS: Thirty eight (58.5%) subjects reported a "lifetime" history of PE. Twenty (30.76%) of them reported "current" history of PE. Eleven (16.9%) people reported that PE preceded opiate misuse. Twenty four (63.2%) felt that heroin helped their PE and 7 (18.4%) felt that heroin worsened it. Fourteen (36.8%) felt that methadone helped PE, while 10 (26.3%) felt methadone worsened PE. Only 2 out of 65 (3.07%) reported that they had been asked about their sex life by the addiction services.
CONCLUSION: Prevalence of "current" premature ejaculation was almost 3 times greater than reported in the general population. A significant number of patients perceived heroin to be beneficial on PE. Presence of sexual dysfunction could therefore be a risk factor for relapse into heroin misuse. Most clinicians avoid asking patients questions of a sexual nature. Nevertheless, managing sexual difficulties among patients with opiate misuse could be a significant step in relapse prevention.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 21920671     DOI: 10.1016/j.addbeh.2011.08.005

Source DB:  PubMed          Journal:  Addict Behav        ISSN: 0306-4603            Impact factor:   3.913


  13 in total

1.  Demographic and clinical factors predicting retention in methadone maintenance: results from an Irish cohort.

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Review 2.  Clinical factors associated with sexual dysfunction among men in methadone maintenance treatment and buprenorphine maintenance treatment: a meta-analysis study.

Authors:  A Yee; H S Loh; H M B Hisham Hashim; C G Ng
Journal:  Int J Impot Res       Date:  2014-07-03       Impact factor: 2.896

Review 3.  Urological complications of illicit drug use.

Authors:  Sean C Skeldon; S Larry Goldenberg
Journal:  Nat Rev Urol       Date:  2014-02-18       Impact factor: 14.432

Review 4.  Sexual dysfunction in patients with alcohol and opioid dependence.

Authors:  Sandeep Grover; Surendra K Mattoo; Shreyas Pendharkar; Venkatesh Kandappan
Journal:  Indian J Psychol Med       Date:  2014-10

5.  Erectile dysfunction in methadone maintenance patients: a cross sectional study in northern iran.

Authors:  Seyed Hamzeh Hosseini; Ali Isapour; Mehrdad Tavakoli; Mehrdad Taghipour; Meysam Rasuli
Journal:  Iran J Psychiatry       Date:  2013-10

Review 6.  Sexual Dysfunction in Inflammatory Bowel Disease: What the Specialist Should Know and Ask.

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Journal:  Int J Gen Med       Date:  2021-05-24

7.  Sexual dysfunction improved in heroin-dependent men after methadone maintenance treatment in Tianjin, China.

Authors:  Minying Zhang; Huifang Zhang; Cynthia X Shi; Jennifer M McGoogan; Baohua Zhang; Linglong Zhao; Mianzhi Zhang; Keming Rou; Zunyou Wu
Journal:  PLoS One       Date:  2014-02-10       Impact factor: 3.240

8.  When higher doses in opioid replacement treatment are still inadequate - association to multidimensional illness severity: a cohort study.

Authors:  Jens Reimer; Eduard Boniakowski; Christian Bachner; Bernd Weber; Wieland Tietje; Uwe Verthein; Stephan Walcher
Journal:  Subst Abuse Treat Prev Policy       Date:  2014-02-28

9.  Female Sexual Dysfunction Among the Wives of Opioid-Dependent Males in Iran.

Authors:  Marjan Anvar Abnavi; Jamshid Ahmadi; Sajedeh Hamidian; Sara Ghaffarpour
Journal:  Int J High Risk Behav Addict       Date:  2016-02-29

10.  Sexual Dysfunction in Heroin Dependents: A Comparison between Methadone and Buprenorphine Maintenance Treatment.

Authors:  Anne Yee; Mahmoud Danaee; Huai Seng Loh; Ahmad Hatim Sulaiman; Chong Guan Ng
Journal:  PLoS One       Date:  2016-01-28       Impact factor: 3.240

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