| Literature DB >> 21919533 |
Panawan Moosophon1, Somdej Kanokmedhakul, Kwanjai Kanokmedhakul.
Abstract
Three new diarylpropanes (1-3), a new arylpropyl quinone (4), and the known 1-(2-hydroxy-4-methoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)propane (5) were isolated from a methanol extract of stems of Combretum griffithii. Their structures were elucidated by spectroscopic methods. Compounds 1, 2, 4, and 5 showed cytotoxicity against one or more cancer cell lines (KB, MCF7, and NCI-H187), and compound 5 exhibited activity against Mycobacterium tuberculosis (MIC 3.13 μg/mL).Entities:
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Year: 2011 PMID： 21919533 DOI： 10.1021/np200593d
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050