| Literature DB >> 21919472 |
Chuan-Chung Chung1, Medel Manuel L Zulueta, Laxmansingh T Padiyar, Shang-Cheng Hung.
Abstract
An efficient chemical synthesis of mycothiol involving the regioselective ketopinyl desymmetrization of 2,4,5,6-tetrabenzylated D-myo-inositol as the key step is described. Together with a highly α-stereoselective D-glucosaminylation, the whole procedure was accomplished in eight steps with an overall yield of 40%.Entities:
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Year: 2011 PMID： 21919472 DOI： 10.1021/ol202218n
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005