Literature DB >> 21918891

[The significance of extended pelvic lymphadenectomy in bladder cancer].

M Autenrieth1, M Retz, J E Gschwend.   

Abstract

Despite radical surgery, invasive urothelial carcinoma has a high risk of systemic progression. This might be due to the presence of occult but already disseminated tumor cells in lymph nodes, blood, or bone marrow. In all retrospective series presented here, extended pelvic lymphadenectomy seems to provide a clear benefit for survival in pN0 and pN+ patients. Lymph node density and absolute number of positive lymph nodes appear to affect patient outcome and survival. However, only the randomized, prospective German LEA study will hopefully provide conclusive new data.

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Year:  2011        PMID： 21918891     DOI： 10.1007/s00120-011-2665-9

Source DB:  PubMed          Journal:  Urologe A        ISSN： 0340-2592            Impact factor:   0.639


  12 in total

1.  Cystectomy for transitional cell carcinoma of the bladder: results of a surgery only series in the neobladder era.

Authors:  Richard E Hautmann; Jürgen E Gschwend; Robert C de Petriconi; Martina Kron; Bjoern G Volkmer
Journal:  J Urol       Date:  2006-08       Impact factor: 7.450

2.  Lymphadenectomy in patients with transitional cell carcinoma of the urinary bladder; significance for staging and prognosis.

Authors:  J Leissner; R Hohenfellner; J W Thüroff; H K Wolf
Journal:  BJU Int       Date:  2000-05       Impact factor: 5.588

3.  Long-term follow-up of bladder cancer patients with disseminated tumour cells in bone marrow.

Authors:  Margitta Retz; Jens Rotering; Roman Nawroth; Alexander Buchner; Michael Stöckle; Juergen E Gschwend; Jan Lehmann
Journal:  Eur Urol       Date:  2010-12-22       Impact factor: 20.096

4.  Lymph node density affects cancer-specific survival in patients with lymph node-positive urothelial bladder cancer following radical cystectomy.

Authors:  Matthias May; Edwin Herrmann; Christian Bolenz; Arne Tiemann; Sabine Brookman-May; Hans-Martin Fritsche; Maximilian Burger; Alexander Buchner; Christian Gratzke; Christian Wülfing; Lutz Trojan; Jörg Ellinger; Derya Tilki; Christian Gilfrich; Thomas Höfner; Jan Roigas; Mario Zacharias; Sven Gunia; Wolf F Wieland; Markus Hohenfellner; Maurice S Michel; Axel Haferkamp; Stefan C Müller; Christian G Stief; Patrick J Bastian
Journal:  Eur Urol       Date:  2011-01-28       Impact factor: 20.096

5.  Outcomes in patients with urothelial carcinoma of the bladder with limited pelvic lymph node dissection.

Authors:  Nivedita Bhatta Dhar; Steven C Campbell; Craig D Zippe; Ithaar H Derweesh; Alwyn M Reuther; Amr Fergany; Eric A Klein
Journal:  BJU Int       Date:  2006-09-06       Impact factor: 5.588

6.  Does extended lymphadenectomy increase the morbidity of radical cystectomy?

Authors:  C Brössner; A Pycha; A Toth; C Mian; W Kuber
Journal:  BJU Int       Date:  2004-01       Impact factor: 5.588

Review 7.  Improving the prognosis of patients after radical cystectomy. Part I: the role of lymph node dissection.

Authors:  Henrik Suttmann; Jörn Kamradt; Jan Lehmann; Michael Stöckle
Journal:  BJU Int       Date:  2007-12       Impact factor: 5.588

8.  Outcome after radical cystectomy with limited or extended pelvic lymph node dissection.

Authors:  Nivedita Bhatta Dhar; Eric A Klein; Alwyn M Reuther; George N Thalmann; Stephan Madersbacher; Urs E Studer
Journal:  J Urol       Date:  2008-01-25       Impact factor: 7.450

9.  Radical cystectomy and extended pelvic lymphadenectomy: survival of patients with lymph node metastasis above the bifurcation of the common iliac vessels treated with surgery only.

Authors:  Kenneth Steven; Asger L Poulsen
Journal:  J Urol       Date:  2007-08-14       Impact factor: 7.450

Review 10.  Chemotherapy in the post-MVAC era: the case for adjuvant chemotherapy.

Authors:  Jan Lehmann; Margitta Retz; Michael Stöckle
Journal:  World J Urol       Date:  2002-02-27       Impact factor: 4.226
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  2 in total

1.  Laparoscopic radical cystectomy: initial experience using the single-incision triangulated umbilical surgery (SITUS) technique.

Authors:  M Horstmann; M Kugler; A G Anastasiadis; U Walcher; T Herrmann; U Nagele
Journal:  World J Urol       Date:  2012-07-21       Impact factor: 4.226

Review 2.  [Cystectomy in the elderly patient].

Authors:  G Bartsch; K Gust; S Vallo; C Bartsch; I Tsaur; J Mani; A Haferkamp
Journal:  Urologe A       Date:  2013-06       Impact factor: 0.639
  2 in total

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