Literature DB >> 21918786

5-Hydroxymethylcytosine-selective oxidation with peroxotungstate.

Akimitsu Okamoto1, Kaori Sugizaki, Akiko Nakamura, Hiroyuki Yanagisawa, Shuji Ikeda.   

Abstract

Tungsten oxidation worked as a simple chemical reaction for the effective detection of 5-hydroxymethylcytosine in DNA, distinguishing it from its epigenetic precursors, 5-methylcytosine and unmethylated cytosine. The tungsten-oxidation product obtained from 5-hydroxymethylcytosine was trihydroxylated thymine and was detected as a cleavage band in gel electrophoresis after treatment with hot piperidine. This journal is © The Royal Society of Chemistry 2011

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Year:  2011        PMID： 21918786     DOI： 10.1039/c1cc14782j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Rapid and highly specific detection of site-specific 5-hydroxymethylcytosine based on peroxotungstate oxidation and mismatch ligation-based LAMP.

Authors:  Zhenhao Zhang; Tong He; Yan Qi; Yuxuan Dai; Kejing Lao; Xingchun Gou
Journal:  RSC Adv       Date:  2022-07-07       Impact factor: 4.036

2.  Bisulfite-Free, Nanoscale Analysis of 5-Hydroxymethylcytosine at Single Base Resolution.

Authors:  Hu Zeng; Bo He; Bo Xia; Dongsheng Bai; Xingyu Lu; Jiabin Cai; Lei Chen; Ankun Zhou; Chenxu Zhu; Haowei Meng; Yun Gao; Hongshan Guo; Chuan He; Qing Dai; Chengqi Yi
Journal:  J Am Chem Soc       Date:  2018-10-04       Impact factor: 15.419

3.  Fragmentation of a Monoclonal Antibody by Peroxotungstate.

Authors:  Hasitha Rathnayaka; Olivier Mozziconacci; Alavattam Sreedhara; Christian Schöneich
Journal:  Pharm Res       Date:  2018-09-25       Impact factor: 4.200

4.  Bisulfite-free and base-resolution analysis of 5-methylcytidine and 5-hydroxymethylcytidine in RNA with peroxotungstate.

Authors:  Fang Yuan; Ying Bi; Paulina Siejka-Zielinska; Ying-Lin Zhou; Xin-Xiang Zhang; Chun-Xiao Song
Journal:  Chem Commun (Camb)       Date:  2019-02-19       Impact factor: 6.222

5.  A novel method to analyze 5-hydroxymethylcytosine in CpG sequences using maintenance DNA methyltransferase, DNMT1.

Authors:  Saori Takahashi; Isao Suetake; Jan Engelhardt; Shoji Tajima
Journal:  FEBS Open Bio       Date:  2015-09-08       Impact factor: 2.693
  5 in total

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