Literature DB >> 21918744

[Modern three-dimensional conformal craniospinal radiotherapy].

Zsolt Sebestyén1, Péter Kovács, Akos Gulybán, Róbert Farkas, Szabolcs Bellyei, András Szigeti, Dóra Földvári Gallainé, László Mangel.   

Abstract

The main problem of craniospinal irradiation (CSI) is the matching of the fields. The use of a suitable technique is very important because matching of the fields is necessary to use for the optimal cancer irradiation of the long planning target volume (PTV). Since 2007, 8 patients have received CT-based, 3D-planned conformal CSI in our Institute. Patient immobilization was made in prone position in a vacuum bed, using skull and pelvis masks. Organ-at-risk (OAR) contours were made by radiographers. PTV was contoured by radiation oncologists. The prescribed dose to the PTV was 36 Gy with 1.8 Gy dose per fraction. In the planning process the following aspects were taken under consideration: all points of the PTV had to receive at least 95% of the prescribed dose (according to ICRU 50, 62); at junction field edges the overlapping parts were eliminated using a multisegmental technique, where the adjacent segment ends of the neighbouring fields were shifted two times 2 cm, so that the three equally weighted segments used in one field had 2-2 cm distance from each other. In the CSI planning the shape of the patient and so the length of the PTV has made a big emphasis on determining the number of field matching. Thus in some cases instead of two, only one field matching was sufficient - this could be achieved by increasing the source-to-skin distance (SSD) of the fields. The verification made with a solid-water phantom justified the precision of the field matching. The offset used at junction field edges in between one treatment facilitates the verification of field matching - and so the patient positioning. Thus the possibility of having overdosed regions could be reduced, which was very important from a radiation biological point of view.

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Year:  2011        PMID: 21918744     DOI: MagyOnkol.2011.55.3.187

Source DB:  PubMed          Journal:  Magy Onkol        ISSN: 0025-0244


  2 in total

1.  Assessment of the results and hematological side effects of 3D conformal and IMRT/ARC therapies delivered during craniospinal irradiation of childhood tumors with a follow-up period of five years.

Authors:  Zoltán Lőcsei; Róbert Farkas; Kornélia Borbásné Farkas; Klára Sebestyén; Zsolt Sebestyén; Zoltán Musch; Ágnes Vojcek; Noémi Benedek; László Mangel; Gábor Ottóffy
Journal:  BMC Cancer       Date:  2020-07-29       Impact factor: 4.430

2.  Pineoblastoma in Adults: A Rare Case Successfully Treated with Multimodal Approach Including Craniospinal Irradiation Using Helical Tomotherapy.

Authors:  Simona Gaito; Marcella Malagoli; Roberta Depenni; Giacomo Pavesi; Alessio Bruni
Journal:  Cureus       Date:  2019-10-07
  2 in total

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