Literature DB >> 2191819

Stable isotopes in clinical pharmacokinetic investigations. Advantages and disadvantages.

T R Browne1.   

Abstract

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Year:  1990        PMID： 2191819     DOI： 10.2165/00003088-199018060-00001

Source DB:  PubMed          Journal:  Clin Pharmacokinet        ISSN： 0312-5963            Impact factor:   6.447


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  34 in total

1.  New pharmacokinetic methods. III. Two simple test for "deep pool effect".

Authors:  T R Browne; D J Greenblatt; G E Schumacher; G K Szabo; J E Evans; B A Evans
Journal:  J Clin Pharmacol       Date:  1990-08       Impact factor: 3.126

2.  Applications to analytic chemistry: an evaluation of stable isotopes in mass spectral drug assays.

Authors:  W A Garland; M P Barbalas
Journal:  J Clin Pharmacol       Date:  1986 Jul-Aug       Impact factor: 3.126

3.  Estimation of the elimination half-life of a drug at any serum concentration when the Km and Vmax of the drug are known: calculations and validation with phenytoin.

Authors:  T R Browne; D J Greenblatt; J E Evans; G K Szabo; B A Evans; G E Schumacher
Journal:  J Clin Pharmacol       Date:  1987-04       Impact factor: 3.126

4.  Fundamentals of present-day mass spectrometry.

Authors:  C E Costello
Journal:  J Clin Pharmacol       Date:  1986 Jul-Aug       Impact factor: 3.126

5.  The application of stable isotopes to studies of drug bioavailability and bioequivalence.

Authors:  R L Wolen
Journal:  J Clin Pharmacol       Date:  1986 Jul-Aug       Impact factor: 3.126

6.  Staggered stable isotope administration technique for study of drug distribution.

Authors:  J E Evans; T R Browne; D L Kasdon; G K Szabo; B A Evans; D J Greenblatt
Journal:  J Clin Pharmacol       Date:  1985 May-Jun       Impact factor: 3.126

7.  Studies with stable isotopes I: Changes in phenytoin pharmacokinetics and biotransformation during monotherapy.

Authors:  T R Browne; J E Evans; G K Szabo; B A Evans; D J Greenblatt; G E Schumacher
Journal:  J Clin Pharmacol       Date:  1985 Jan-Feb       Impact factor: 3.126

8.  Bioavailability and kinetics of maprotiline.

Authors:  D Alkalay; W E Wagner; S Carlsen; L Khemani; J Volk; M F Bartlett; A LeSher
Journal:  Clin Pharmacol Ther       Date:  1980-05       Impact factor: 6.875

9.  Pharmacokinetic equivalence of stable-isotope-labeled and unlabeled drugs. Phenobarbital in man.

Authors:  T R Browne; A Van Langenhove; C E Costello; K Biemann; D J Greenblatt
Journal:  J Clin Pharmacol       Date:  1982-07       Impact factor: 3.126

10.  Superiority of stable isotope techniques in the assessment of the bioavailability of drugs undergoing extensive first pass elimination. Studies of the relative bioavailability of verapamil tablets.

Authors:  M Eichelbaum; H J Dengler; A Somogyi; G E von Unruh
Journal:  Eur J Clin Pharmacol       Date:  1981-01       Impact factor: 2.953
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  6 in total

1.  Pharmacokinetics and absolute bioavailability of ribavirin in healthy volunteers as determined by stable-isotope methodology.

Authors:  S L Preston; G L Drusano; P Glue; J Nash; S K Gupta; P McNamara
Journal:  Antimicrob Agents Chemother       Date:  1999-10       Impact factor: 5.191

2.  Concurrent assessment of hepatic and intestinal cytochrome P450 3A activities using deuterated alfentanil.

Authors:  E D Kharasch; S Vangveravong; N Buck; A London; T Kim; J Blood; R H Mach
Journal:  Clin Pharmacol Ther       Date:  2011-02-23       Impact factor: 6.875

3.  Dual-Channel Enzymatic Inhibition Measurement (DEIM) Coupling Isotope Substrate via Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry.

Authors:  Min Tao; Li Zhang; Yinlong Guo
Journal:  J Am Soc Mass Spectrom       Date:  2018-08-29       Impact factor: 3.109

Review 4.  Pharmacokinetics of L-carnitine.

Authors:  Allan M Evans; Gianfranco Fornasini
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

5.  Steady-state carbamazepine pharmacokinetics following oral and stable-labeled intravenous administration in epilepsy patients: effects of race and sex.

Authors:  S E Marino; A K Birnbaum; I E Leppik; J M Conway; L C Musib; R C Brundage; R E Ramsay; P B Pennell; J R White; C R Gross; J O Rarick; U Mishra; J C Cloyd
Journal:  Clin Pharmacol Ther       Date:  2012-01-25       Impact factor: 6.875

Review 6.  Stable Isotopically Labeled Intravenous Microdose Pharmacokinetic Trials as a Tool to Assess Absolute Bioavailability: Feasibility and Paradigm to Apply for Protein Kinase Inhibitors in Oncology.

Authors:  Jeroen Roosendaal; Hilde Rosing; Jos H Beijnen
Journal:  Clin Pharmacol Drug Dev       Date:  2020-06-22
  6 in total

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