Literature DB >> 21916429

Total synthesis of (+)-decursivine.

Deqian Sun1, Qiwu Zhao, Chaozhong Li.   

Abstract

The first asymmetric synthesis of natural indole alkaloid (+)-decursivine was accomplished. The key step involves the PIFA-mediated intramolecular [3 + 2] cycloaddition of 5-hydroxytryptophan with a substituted cinnamamide in a highly diastereoselective manner.
© 2011 American Chemical Society

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Year:  2011        PMID: 21916429     DOI: 10.1021/ol2021669

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  C7-derivatization of C3-alkylindoles including tryptophans and tryptamines.

Authors:  Richard P Loach; Owen S Fenton; Kazuma Amaike; Dustin S Siegel; Erhan Ozkal; Mohammad Movassaghi
Journal:  J Org Chem       Date:  2014-11-10       Impact factor: 4.354

2.  Total synthesis of (±)-decursivine via BINOL-phosphoric acid catalyzed tandem oxidative cyclization.

Authors:  Prakash T Parvatkar; Eugene S Smotkin; Roman Manetsch
Journal:  Sci Rep       Date:  2021-10-07       Impact factor: 4.379

  2 in total

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